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Zanocin OD
Last reviewed: 23.04.2024
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Zanocin OD is widely used in infections that have been caused by microorganisms that are sensitive to the drug. These can be problems with the genitourinary system, respiratory tract, skin, tissues and other diseases.
To date, infections of various kinds are widespread, so you need to use an effective tool in dealing with them.
Indications Zanocin OD
Indications for the use of Zanocin OD are the use of the drug during the progression of infectious diseases. Basically, this is a problem with the genitourinary system. The medicine is widely used for acute and chronic pyelonephritis, cystitis, complications after the transferred infections, etc.
In respiratory diseases, the agent is also used. Among the problems with which a medicine can fight, include: pneumonia, chronic bronchitis, pulmonary abscesses, sinusitis and others.
Zanotsin OD struggles with infections of skin tissues, venereal diseases, etc. Often it is used in the complex therapy of osteomyelitis, leprosy, complications in patients with immune deficiency. In some cases, the drug is used for prevention, as well as in the postoperative period of treatment after surgical infections. The scope of the drug is actually broad, it is able to deal with problems of various types. Zanotsin OD is a powerful tool that can cope with any infection.
Release form
The form of release of the drug is standard and is presented by tablets. The only thing they differ from each other is the content of the active substance. The drug is administered solely by mouth.
The main components of the medicine are: cellulose, corn starch, lactose, sodium starch glycolate, polysorbate, magnesium stearate and others. This concerns the "packaging" of 200 mg.
The medicine, which contains 400 mg of active substances, has a slightly different composition. It is supplemented with xanthan gum, sodium alginate, hydracarbonate, carbomer and other components.
Zanotsin OD is also with 800 mg of active substances. The composition is similar to the previous one, but with the addition of silica gel of colloidal anhydrous and lactose monohydrate.
A specific form of output is selected based on specific requirements. So, a lot depends on the human condition and infection, which must be overcome. In general, Zanocin OD has a positive effect in any form.
Pharmacodynamics
Pharmacodynamics - Zanocin OD with prolonged release of the active ingredient ofloxacin. Use the tool can not be more than once a day. Reception, as a rule, is single and does not require a repeat. In general, to achieve a certain therapeutic effect, the drug is used in a "concentration" of 400 or 800 mg. It is possible to take and 2 tablets of 400 mg or 4 to 200 mg. There is no particular difference, the only thing is that the reception is not done at once.
Zanocin OD has a bactericidal effect, which is due to the ability to block the bacterial DNA-gyrase enzyme. As a consequence of this action, there is a violation of the DNA function of the bacteria. The spectrum of "work" of the drug covers many microorganisms.
He perfectly fights infectious agents and blocks their penetration into the body when the drug is used as a prophylaxis. Zanocin OD is able to repel many bacteria, thanks to its unique properties.
Pharmacokinetics
Pharmacokinetics of the drug - quickly absorbed into the digestive tract. Food does not affect the degree of absorption of the drug in any way. Therefore, you can take the remedy at any time. Bioavailability of the drug is 96%.
Tablets of prolonged ofloxacin are absorbed much faster than those that are applied 2 times a day. After using the drug, its maximum concentration in the blood plasma is reached in 6-8 hours. The full half-life is also 6-8 hours.
Ofloxacin is excreted by the kidneys, so its pharmacokinetics significantly changes in those patients who have kidney problems. Hemodialysis can slightly reduce the concentration of the main component in the blood.
Zanocin OD is widely distributed across all tissues and body fluids. The average distribution is 1.0-25 l / kg. 31% of the drug binds to blood plasma proteins.
A high concentration of the substance reaches in most tissues and body fluids. Drug is excreted unchanged, with almost 24-48% excreted in the urine. About 4-8% of Zanocin OD comes with feces.
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Dosing and administration
Dosing and Administration Zanocin OD is appointed by the attending physician. Much depends on the severity of the diseases, as well as the microorganism, which caused a negative reaction of the body. The body weight, age and kidney condition are taken into account. After all, the medicine to some extent causes a negative impact on their functions.
The course of treatment should not exceed 3-14 days. Duration is completely dependent on the condition of the person. If necessary, the period increases by another 2-3 days.
The dose of the drug is 400-800 mg per day. You need to take the medicine at a time. If a person has gonorrhea, then the dose is divided into 2 divided doses of 400 mg each.
If there are problems with the kidneys, the dosage is individual. It depends on the creatinine clearance. If its value is more than 50 ml / min, the usual dose is used. When it is 20-50 ml / min, then a day should not use more than 400 mg of medicament. At a rate of 20 or less ml / min, the drug should not be used.
Patients with severe hepatic impairment should not use more than 400 mg of medicament per day. With an incorrectly calculated dosage, Zanocin OD can cause serious harm.
Use Zanocin OD during pregnancy
Use Zanocin OA during pregnancy should be discussed with your doctor. Naturally, this medication is not recommended. It is able to penetrate the placenta and thus has a negative effect on the development of the fetus.
A similar situation develops with the period of breastfeeding. The active component of the drug can freely enter the baby's body through the mother's milk. Its influence on the developing organism can be detrimental. Therefore, the use of the drug should be fully negotiated with the doctor.
In the early stages of pregnancy, the use of the drug is prohibited. The woman's organism is on the verge of perestroika, it is very vulnerable, therefore various influences from the outside can negatively affect it. Permit this in no case it is impossible.
You can use the medicine under the strict guidance of the attending physician. After all, only he can prescribe a certain dosage or find an alternative way to solve the problem. Take Zanocin OD yourself, you can not!
Contraindications
Contraindications to the use of Zanocin OD mainly consist in the presence of hypersensitivity to certain components of the drug.
But, this is not the whole list. In no case should the remedy be used in case of traumatic brain injury. A similar contraindication applies to people who have suffered a stroke and have problems with the central nervous system. If there is a need to take this drug, then this is done with extreme caution. There is always a way to find an alternative way to solve the problem.
Epilepsy also does not allow the use of a medicament based onloxacin. At a younger age, use of the drug is not recommended. This rule extends mainly to the age of sixteen.
During pregnancy, the use of the drug is prohibited. The period of breastfeeding is included in the list of contraindications. The active component of the drug can freely penetrate through the mother's milk into the child's body. Using Zanotsin OD without special recommendation is not necessary, the drug can cause serious damage to the body.
Side effects Zanocin OD
Side effects of Zanocin OD are very serious. But, if you take the drug correctly, then their appearance should not be worried. So, usually the gastrointestinal organs and the liver start to react negatively. It manifests itself in the form of nausea, diarrhea, vomiting, abdominal pain, and discomfort in the stomach. In more serious cases, anorexia may occur.
The central nervous system is also able to react negatively to the administration of the drug. This manifests itself in the form of headache, insomnia, neuropathy, visual impairment, taste and the appearance of hallucinations. From the side of the cardiovascular system, tachycardia and lowering blood pressure are possible.
There may be problems with blood in the form of thrombocytopenia, anemia and pancytopenia. In extremely rare cases, hemolytic anemia occurs. From the side of the kidneys: acute interstitial nephritis, impaired function, increased creatinine level, etc.
Allergic and skin reactions are possible. As a rule, these are rashes, itching, in rare cases, polymorphic erythema, vasculitis, fever, angioedema and pneumonitis.
There may be a general malaise, increased blood sugar, inflammation and tendon ruptures. All this shows that taking Zanocin OA is necessary with caution.
Overdose
Overdose Zanocin OD is found, but in extremely rare cases. If a person does not independently increase the dose, then nothing terrible will happen to him. True, there were situations when an overdose occurred, despite the fact that the patient took everything according to the set plan.
In some cases, it is possible to develop confusion, the appearance of drowsiness and inhibition. It is possible for dizziness, nausea and vomiting. This occurs when the concentration of the drug in the body is high.
There is no specific antidote, therefore it is necessary to apply standard emergency interventions. The first thing to do is rinsing the stomach. The body needs to be freed from the drug. It is recommended to resort to hemodialysis and peritoneal dialysis.
Naturally, a doctor is necessary. Independently improve the condition is unlikely to succeed. If we do not independently exceed the dose and follow the recommendations of a specialist, Zanocin OD will not cause harm to the body.
Interactions with other drugs
Interactions with other drugs, perhaps he needs to do it with extreme caution. So, the concentration of theophylline in the blood can significantly increase if you take this medication together Zanocin OD. Therefore between the use of these drugs should take at least 4 hours. Especially, if the composition of the other agent is iron, aluminum, magnesium and zinc.
Probenecid, furomesid and cimetidine can delay the process of taking offloxacin from the body. NSAIDs in turn are able to stimulate the effect oflofsaitsnana CNS,
At simultaneous application it is necessary to spend the control over indicators of coagulation. If oral antidiabetics are used, then glycemia is monitored.
If a person takes more than one drug, then the physician should be informed about this. After all, their influence on each other can be unacceptable and lead to serious consequences. Zanotsin OD is a powerful tool that requires complete control over its use.
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Storage conditions
The storage conditions of Zanocin OD are standard and do not differ from the rest. It is important to observe a certain temperature regime, which should not exceed 25 degrees of heat. For this, it is perfect for storage in a room temperature.
The remedy is not whimsical and can be anywhere. The main thing that there was no dampness and direct sunlight. To spoil the medicine is not so simple, so you can leave it anywhere.
It is important not to let the money get to the kids. Medication affects the developing organism negatively. Its use can harm the baby's body. Therefore, for this moment it is necessary to actively monitor.
You can not give the medicine cold, it's also not recommended to freeze it. After this process, it can not be used. It is desirable to simply place the drug in the medicine cabinet. As a rule, all the necessary conditions for storage are observed there. In this case, there is no reason to worry about the expiration date. Zanocin OD is a medication that does not require specific conditions.
Shelf life
The expiration date is important, but it depends entirely on the storage conditions. So, if you follow certain rules, then the medication will last for more than one year. It is important to pay attention to the temperature regime, it should not exceed 25 degrees. Naturally, the figure can fluctuate, but not significantly. Frost is not allowed!
To ensure that the packaging has not been spoiled, it is necessary to protect the product from children's pens. Kids are very curious and in this regard they can harm not only the medicine, but themselves.
The dampness should be under strict control. Heat and high humidity adversely affect the remedy. Therefore, it is better to take care of the optimal storage conditions in advance. In this case, an ordinary first-aid kit will do.
It should be understood that compliance with all conditions can significantly extend the "life" of the medication. If his shell is damaged, then 2-3 years, he obviously will not last. More precisely, it is possible, but the medicine is unlikely to be accepted. Observance of optimal conditions is a pledge of long-term storage of Zanocin OD.
Attention!
To simplify the perception of information, this instruction for use of the drug "Zanocin OD" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.