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VATER-association

 
, medical expert
Last reviewed: 23.04.2024
 
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Epidemiology of VATER-association

1.6 per 10,000 newborns.

trusted-source[1], [2], [3], [4], [5], [6]

Causes of VATER-association

Most cases are sporadic, with no indication of teratogenic or external factors. Several family cases have been described.

trusted-source[7], [8]

Symptoms of VATER-associations

The spectrum of congenital malformations is very wide and more than 2/3 of these defects are located in the lower segment of the body (defects of the distal parts of the intestine, genito-urinary anomalies, pelvic bone and lower limbs). Defects of the upper body segment include atresia of the esophagus, various defects of the radiation structures, congenital heart and upper respiratory tract defects.

Symptomatic complex of congenital malformations:

  • Vertebral defects (congenital malformations of the spine - non-growth of the arches, butterfly-shaped vertebrae) - 70%;
  • Anus atresia - 80%;
  • Tracheo-esophagial fistula - 70%;
  • Renal defects - kidney defects or Radial defects - aplasia / hypoplasia of the radial structures of the hand - 65%.

Diagnosis of VATER-association

Diagnostic criteria: the presence of 3 out of 5 listed above congenital malformations with a normal chromosome set.

trusted-source[9], [10], [11], [12], [13], [14]

What tests are needed?

Treatment of VATER-association

Symptomatic treatment.

Features of management of patients

When combined with a newborn atresia, the anus with abnormalities of the spine or hand is carefully inspected for tracheoesophageal fistula.

When the neonatal pathology of the esophagus and the radial structures of the hand are combined, it is necessary to exclude congenital malformations of the kidneys.

trusted-source[15]

Forecast

It is determined by the spectrum and severity of the identified congenital malformations. The intellect is saved.

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