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Treatment for joint pain

Medical expert of the article

Orthopedist, onco-orthopedist, traumatologist
, medical expert
Last reviewed: 04.07.2025

In the treatment of systemic joint diseases, which mainly include inflammatory diseases of the musculoskeletal system, several components are distinguished.

Topical therapy (pain relief): NSAIDs - nimesulide (remesulide), meloxicam (revmoxicam), ketoprofen (ketonal), diclofenac (diclak); a group of opioid analgesics such as tramap, tramadol; glucocorticoid drugs.

Until recently, it was believed that when conducting topical therapy aimed at relieving pain syndrome, it is necessary to use either only the NSAID group (diclac) or only the tramadol group. Experience shows that using both groups simultaneously leads to a summarily greater effect. The additional prescription of tramadol enhances the effect of NSAIDs and allows for a reduction in their dose.

Basic drugs: cytostatics (methotrexate, cyclophosphamide), quinoline and sulfonamide drugs, immunotropic drugs (immunomodulators, anticytokine agents). In the treatment of metabolic-dystrophic diseases of the joints, the basic therapy includes a group of chondroprotective drugs (teraflex).

Additional therapy: local therapy, extracorporeal detoxification, vitamin therapy, physiotherapy.

A fairly large list of extracorporeal treatment methods used today has its own limited indications, which include a high degree of activity of the immune-inflammatory process, including local inflammation with the presence of lesions of many joints at once and the lack of effect from previous therapy.


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