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The reasons for raising and lowering basophils

Medical expert of the article

Hematologist, oncohematologist
, medical expert
Last reviewed: 19.10.2021

Basophilia - an increase in the number of basophils in the blood (more than 0.2 × 10 9 / l). Diseases and conditions in which basophilia is possible include:

  • allergic reactions (for food, lekartsva, introduction of foreign protein);
  • chronic myelogenous leukemia, myelofibrosis, erythremia;
  • lymphogranulomatosis;
  • chronic ulcerative colitis;
  • hypothyroidism of the thyroid gland;
  • treatment with estrogens.

In addition to the above reasons for basophilia, it is possible during ovulation and pregnancy. Sometimes basophilia occurs due to iron deficiency, lung cancer, anemia of unknown genesis, true polycythemia, some hemolytic anemias, and after splenectomy.

Basopenia is a decrease in the number of basophils in the blood (less than 0.01 × 10 9 / L). Basopenia is difficult to evaluate because of the low basophil content in the norm.


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