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Potassium-normin
Medical expert of the article
Last reviewed: 03.07.2025

A medicine that helps eliminate potassium deficiency in the human body - Potassium-normin. This drug was developed and is produced by the joint Hungarian-German pharmaceutical corporation Alkaloid Chemical Company ZAO for "MEDA Pharma GmbH & Co. KG".
ATC classification
Active ingredients
Pharmacological group
Pharmachologic effect
Indications Potassium-normin
The drug in question was specially developed and released as a drug with a narrow action. Indications for the use of Potassium-normin are the relief of the problem of deficiency of such an essential microelement as potassium, which causes hypokalemia when it is deficient. The genesis of this problem may be different:
- Various types of diseases that cause calcium loss.
- Long-term use of diuretics. Potassium is also washed out of the body along with urine.
- Taking medications from other pharmacological groups: cardiac glycosides, glucocorticosteroids.
- Vomit.
- Symptoms of diarrhea such as loose stools.
- Prevention of hypokalemia.
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Release form
The manufacturing company produces the drug in question only in tablet form – this is, to date, its only form of release.
It is worth noting that modern tablet forms of Potassium-normin have a prolonged type of action.
The unit of the drug has a rounded shape with convex sides on both sides. The drug is produced in a white shade. The tablet is bitter in taste, without a clear smell.
The main active ingredient of the drug is potassium chloride (kalii chloridum), the concentration of which in a unit of medicine is 1 g, which is equivalent to 524.44 mg of potassium ions.
Additional chemical compounds that are elements of the medicinal unit are: cetyl alcohol (0.017 g), talc (0.008 g), polyvinyl butyral (0.0575 g), anhydrous colloidal silicon dioxide (0.01 g), magnesium stearate (0.001 g).
The medicine itself, Potassium-normin, can be found on the shelves of drugstores packed in blasters of ten units. The cardboard packaging, which always includes a leaflet with recommendations for the use of the drug, contains three such blasters. That is, the package contains 30 tablets of Potassium-normin.
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Pharmacodynamics
The main active ingredient of the drug under consideration, Potassium-normina, is potassium chloride. It is its pharmacological properties that determine the pharmacodynamics of this drug.
Potassium chloride inhibits myocardial excitability, effectively reducing its conductivity. This substance inhibits the toxicological manifestations of cardiac glycosides, while remaining inert to their positive inotropic function.
When introducing minor doses of potassium chloride, an increase in the flow cross-section of the coronary vessels is observed. At the same time, as studies have shown, large blood vessels, on the contrary, reduce this indicator.
Potassium - Normin normalizes the level of conductivity of nerve impulses and activates the synthesis and work of numerous cytoplasmic enzymes. Potassium chloride monitors and normalizes the process of protein synthesis, normalizes osmotic tension inside the cell, participates in the transportation of amino acids throughout the body.
Potassium-normin has a positive effect on the work of skeletal muscles, causing them to contract more actively, removing the diagnosis of myasthenia (a genetic pathology manifested by rapid fatigue of striated muscles) or muscular dystrophy.
Pharmacokinetics
When introducing a specific drug into the treatment protocol, in addition to the pharmacological dynamics of the drug, the specialist treating the disease is also interested in its pharmacokinetics. An important factor in any therapy is the ability of the drug, in this case Potassium - Normin, to be quickly absorbed by the mucous membrane, and also the ability of the body to effectively remove the remains or metabolites of the drug from the patient's body is not the least important factor.
After the drug has entered the body through the oral cavity, it is absorbed by the mucous membrane quite quickly and with a large quantitative percentage. The level of adsorption of this drug is about 70%. At the same time, the analysis of clinical studies has shown that the concentration of potassium chloride gives significantly higher indicators in the small intestine than in blood plasma.
As the tablet passes through the digestive tract, it gradually and slowly dissolves, and the active ingredient is released, ready to “work”.
In the ileum and large intestine, potassium ions (K + ) "switch places" with positive sodium ions (Na + ), which allows them to be excreted from the body together with urine. With urine, through the kidneys, one tenth of the microelement leaves the body.
After being introduced into the body, potassium chloride undergoes a distribution process over the next eight hours.
The half-life of the drug elements Potassium - Normin (T 1/2 ) against the background of adsorption is on average 1 hour 20 minutes. This indicator of release from a unit of the drug retard (slowing down of biological processes) passes in time about six hours.
Dosing and administration
Any person must know that a medicinal product, including Potassium-normin, must be prescribed only by a qualified experienced specialist. The developers of the drug have only suggested the recommended method of administration and doses of the drug in question, and a more specific schedule of administration, method of treatment and dosage adjustment remains with the attending specialist.
The manufacturer recommends taking tablets orally in a daily dosage of 1–2 g (depending on the clinical picture of the pathology and the individual characteristics of the patient’s body).
If therapeutic effectiveness has not been achieved and the situation requires adjustment of the daily dose, it is possible to increase it to 6 g, but not more.
The duration of treatment is determined by the attending physician individually. And only he can prescribe the medicine, adjust its dosage, and cancel its use.
Use Potassium-normin during pregnancy
Any normal woman who is pregnant or lactating ensures that her body receives as few substances as possible that can affect the natural course of fetal development. But one should not forget about the woman's health, because this factor can cause problems both in the development of the baby and during obstetrics.
To date, the level of influence of the drug in question on the embryo, its formation and development has not yet been fully studied. Therefore, the use of the drug Potassium - Normin during pregnancy is not recommended by doctors and pharmacists.
An exception may be a situation where the medical need to help the health of the expectant mother outweighs the possible risk that threatens the development of the baby.
This is due to the lack of data on the potential for negative effects and penetration of Potassium-normin into breast milk, doctors recommend that if at the time of the necessary therapy a woman is breastfeeding a newborn, feeding should be interrupted.
During treatment, wean the baby from the breast and switch him to feeding with special adapted formulas.
Contraindications
A pharmaceutical product is a medicine because it is capable of exerting a certain effect on the patient's body. And this effect, when targeted at relieving one problem, does not always affect other areas and systems of the human body, affecting their functionality.
Contraindications to the use of the drug Potassium-normin are reflected in the list below:
- Hyperkalemia is a pathological condition resulting from an increase in the concentration of potassium in the extracellular fluid and blood plasma.
- Increased individual intolerance of the patient's body to one or more components of Potassium - Normin.
- Tendency to allergic reactions.
- Kidney dysfunction that has progressed to the stage of chronic disease.
- Complete AV block is a disruption of the transmission of nerve impulses in the cardiac conduction system.
- Adrenal dysfunction.
- Hypovolemia (decreased total blood volume) with hyponatremia (significant decrease in serum sodium concentration).
- Erosive and ulcerative lesions of the gastric mucosa and duodenum.
- Acidosis is an excessive increase in blood acidity.
- Therapy accompanying the use of potassium-sparing diuretics.
- The period during which a woman bears a child.
- Lactation time.
- It is not allowed to take the drug Potassium-normin if the patient is under 18 years of age.
Side effects Potassium-normin
Mostly, the medicine is well tolerated by the patient's body. However, in some cases, side effects of the drug in question may occur.
Due to individual characteristics of the body, Potassium-normin can provoke:
1. The appearance of nausea in the epigastric region, which, if intense, can provoke vomiting.
2. Confusion.
3. Loose stools, diarrhea, urge to defecate more than three times a day.
4. The appearance of internal gastrointestinal bleeding.
5. Allergy to the drug.
6. Abdominal pain syndrome.
7. Drop in blood pressure.
8. Perforation of the gastrointestinal mucosa.
9. Decreased muscle tone.
10. Intestinal obstruction.
11. Paresthesia – a disturbance in the sensitivity of the skin, numbness of the extremities.
12. Blockade or complete cardiac arrest.
13. Hyperkalemia is an excessively high amount of potassium in the extracellular fluid and blood plasma.
Overdose
As clinical observations have shown, an overdose of the leading active chemical component of Potassium-normin, which is potassium chloride, is quite possible both due to an excess of the administered amount of the substance and due to the individual susceptibility of the patient's body. In this case, the patient's body reacts to this with a response pathological symptomatology:
1. The emergence of factors indicating the occurrence and development of hyperkalemia. It is worth remembering that this complication can develop asymptomatically and lead to death in a short period of time. Therefore, regular monitoring of potassium ion levels in the body is necessary during therapy.
- Decreased speed of impulses conducted by myocardial muscles.
- Decreased muscle tone.
- Numbness of the limbs, impaired skin sensitivity.
- Disruptions in the rhythm of the heart, up to and including its arrest.
There is currently no single antidote that can completely stop the problem. Treatment is symptomatic. If necessary, peritoneal dialysis or hemodialysis can be included in the resuscitation protocol.
Interactions with other drugs
Very often the drug in question, Potassium-normin, is introduced into the protocol of therapy of complex treatment of the disease. When prescribing this drug, the attending physician must be aware of which pharmacological structures can be combined into one therapeutic protocol, and which, when administered together, can only aggravate the situation.
It is necessary to know the interactions with other drugs and the drug in question Potassium - Normin.
As clinical observations have shown, the administration of potassium chloride reduces the quantitative and qualitative intensity of side effects of cardiac glycosides.
Concomitant use (or if such tandem administration is necessary, strict monitoring of the process is required) of Potassium-normin with drug groups of potassium-sparing diuretics, ACE (angiotensin-converting enzyme) inhibitors, directly potassium-based drugs, as well as non-steroidal anti-inflammatory drugs should not be allowed. This caution is due to the fact that the joint work of such pairs increases the likelihood of developing hyperkalemia.
With the tandem administration of Potassium-normin and quinidine, monitoring of the therapy process shows an increase in the pharmacological characteristics of the latter.
But when paired with disopyramide, the results of their use show an increase in the symptoms of disopyramide side effects.
Storage conditions
In order for the treatment to bring maximum effect, it is necessary to carefully follow not only the recommendations and requirements of the attending physician who prescribed the therapy, but it would also be useful to get acquainted with and follow the storage conditions of Potassium - Normin, which are necessarily described in the leaflet - instructions attached to any pharmacological agent. If the drug is stored incorrectly, the effectiveness of its application in the therapy protocol can be significantly reduced.
If you follow absolutely all the recommendations, you can be sure that the drug will effectively “serve” for the entire period of the permissible shelf life determined by the specialists of the manufacturing company.
The drug should be stored in accordance with the following requirements:
- The place where Potassium-normin is to be stored must be protected from direct sunlight.
- The room temperature must be within acceptable limits: from + 15 to + 30 degrees above zero.
- The humidity percentage is quite low.
- The medicine must be kept in places that are inaccessible to teenagers and small children.
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Shelf life
Any product released by a corporation-manufacturer entering the pharmacy market must be provided on the packaging material with date indicators indicating when the given medicinal product was produced. The second number marks the end date, after which the medicinal product in question should not be used to treat a particular disease.
When Potassium-normin was released, the expiration date was set at 3 years from the date of production of the drug.
Manufacturer
Attention!
To simplify the perception of information, this instruction for use of the drug "Potassium-normin" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.