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Ovulatory syndrome
Medical expert of the article
Last reviewed: 04.07.2025
This is a disorder in which ovulation is accompanied by subjective symptoms in the form of pain or discomfort in the lower abdomen, uterine discharge, which should not normally be present.
Ovulatory syndrome is a pathology that any woman can encounter in her life. Due to the prevalence of hormonal disorders in women of reproductive age today, this syndrome is common. As a rule, this syndrome does not cause any pathological disorders in the reproductive system, but sometimes the symptoms can be expressed strongly, disrupting the normal life of a woman. It is necessary to know the main signs of this syndrome and methods of its correction in order to know how to help yourself.
Epidemiology
Every third woman has a permanent ovulatory syndrome. Every second woman has encountered manifestations of this syndrome at least once in her life. In percentage terms, more than 85% of women with menstrual cycle disorders have problems with pronounced ovulatory syndrome. But strangely enough, more than 30% of women, having symptoms of ovulatory syndrome, do not know what it is about and do not consult a doctor, considering this a normal phenomenon.
Causes ovulatory syndrome
The main reason for the development of ovulatory syndrome is the entry of blood into the peritoneum receptors. Given these pathogenetic mechanisms, there is no need to talk about a pathological process. Therefore, the treatment of this syndrome is not mandatory and depends entirely on the severity of the clinical picture. If we are talking about the development of complications associated with this syndrome, then it has a different direction.
Risk factors
When talking about the main causes of this syndrome, it is necessary, first of all, to find out the risk factors, having which one can assume a high probability of developing pathology. Risk factors include all pathologies that are accompanied by a violation of the normal structure and function of the ovaries and uterus:
- Ovarian cysts - they occur when the proliferation of ovarian cells or the corpus luteum is disrupted. This is directly related to hormonal changes, so if this pathology is present, the risk of disorders associated with the maturation of the egg and its release also increases.
- Chronic inflammatory diseases of the ovaries - they cause the formation of adhesions on the ovary and this in turn disrupts the normal release of the egg from the follicle.
- Disorders of the ovariomenstrual cycle of a central or peripheral nature - this also disrupts the functioning of the endometrium and its regulation with the development of characteristic symptoms.
- Algomenorrhea in women - painful menstruation increases the risk of developing pain syndrome during ovulation, since the nervous regulation of this process is primarily disrupted.
- A history of frequent abortions increases the risk of developing adhesions and disrupts normal ovulation.
All these risk factors can disrupt normal ovulation through hormonal imbalance or local changes. Therefore, when talking about ovulatory syndrome, it is necessary to determine how the ovulation process normally occurs.
Ovulation is the process of the release of an egg from the follicle after its maturation. Normally, this process occurs at the peak of changes in the level of various hormones. At the same time, the amount of follicle-stimulating hormone and estrogens decreases, which causes a gradual increase in progesterone and luteinizing hormone - it is at the peak of its increased concentration that the follicle ruptures. Ovulatory syndrome occurs when the rupture of the follicle occurs against the background of insufficient concentration of certain hormones. Therefore, the main cause of ovulatory syndrome is a rapid rupture of the follicle, which is accompanied by blood getting outside the uterine space onto the peritoneum - this leads to its irritation and the appearance of symptoms.
Pathogenesis
The pathogenesis of the development of this syndrome also lies in the presence of local adhesions of the tubes or ovaries, which leads to incorrect movement of the egg - not into the ampullar part of the tube, but into the pelvic cavity, since there is an obstacle to its movement and even the fimbriae do not correct this process.
The development of symptoms is also caused by other changes. During ovulatory syndrome, there is also a hormonal imbalance, which does not normally occur. But in this case, when the follicle ruptures, the amount of estrogens synthesized by the egg decreases, and a sufficient amount of progesterone has not yet been produced. Therefore, initial small changes occur at the level of the endometrium. It can peel off in some places at the level of the functional layer, which leads to the development of the corresponding clinical picture.
Symptoms ovulatory syndrome
It is difficult to argue with the fact that ovulatory syndrome is a pathology. It is not accompanied by any organic changes in the uterus or ovaries and does not interfere with the process of normal pregnancy, so it is not considered a disease. But as the symptoms become more severe, it can cause functional problems. After all, normally the ovulation process is almost imperceptible, especially since there are no painful sensations. Some women do not even suspect when exactly they ovulate. And some may feel a slight increase in secretion in the form of an increase in serous discharge from the uterus. The stages of ovulation development are the gradual growth of the egg from the primordial follicle to the tertiary, when full maturation and its exit from the membranes for fertilization occur.
The first signs of ovulatory syndrome may appear already after the age of twenty, when menstruation becomes regular. Girls, as a rule, do not suffer from this pathology. This syndrome is characterized by lability - it can disappear, for example, after childbirth or appear for the first time after it. In the presence of risk factors, this symptom can appear in such compromising situations and disappear just as suddenly.
Then the first clinical manifestations of this syndrome appear. The most pronounced symptom is pain in the lower abdomen, usually one-sided. This pain occurs due to irritation of the peritoneum by blood particles that get in when the follicle ruptures. In this case, the pathognomonic symptom is the occurrence of pain on the 13th-14th day of the menstrual cycle, if it lasts 28 days, or the coincidence of such pain with ovulation with a different cycle duration. Such pain can have varying degrees of severity - from mild to very pronounced. It depends on the degree of irritation and the amount of fluid that got on the peritoneum. The process is one-sided, because ovulation most often occurs due to the rupture of one follicle.
Also, the second most pronounced symptom is vaginal discharge of a bloody nature. They are not massive and, as a rule, insignificant - these are manifestations of relative hypoestrogenism against the background of insufficient stimulation of the ovaries and partial detachment of the functional layer of the endometrium. Such discharge can also be serous.
The duration of ovulatory syndrome should not be more than two days, otherwise we may be talking about another serious pathology.
Ovulatory syndrome with a temperature within the normal range may manifest itself as a slight increase of no more than one degree. This is due to the fact that normally the ovulation process occurs with an increase in basal temperature under the influence of luteinizing hormone, but it does not exceed 0.8 degrees. If we are talking about ovulatory syndrome, then such an increase in temperature may be systemic due to the reaction of the hormonal background and an increase in the level of catecholamines. But it is very important that such an increase in temperature should not last more than a day and should not exceed 38 degrees. If the increase in temperature is strong and prolonged, then it is necessary to immediately think about the development of acute abdomen. This is very important for timely diagnosis of pathology and conducting a clear differential diagnosis.
Psychosomatics in ovulatory syndrome is of great importance for assessing the severity of manifestations. After all, against the background of increased emotional inconsistency, there is an increase in the production of catecholamines - stress hormones. They, in turn, contribute to the development of increased blood circulation in the uterus and ovaries - this can cause an increased reaction when the follicle ruptures and minor local bleeding, which will cause symptoms of ovulatory syndrome. Therefore, increased emotionality of a woman also contributes to this syndrome, as well as constant stress. Increased severity of symptoms can be aggravated by increased emotionality, so these are interrelated processes, which must be taken into account when correcting this condition and include in the complex drugs that are aimed at reducing nervous excitability.
Complications and consequences
Complications that may arise with ovulation disorders are mainly associated with incorrect and untimely differential diagnostics. If acute abdominal pain is incorrectly interpreted, serious inflammatory complications may arise.
The consequences of ovulatory syndrome can be expressed mainly in the disruption of the woman's daily activity, decreased libido and the development of depressive thoughts during this period. If ovulatory disorders are caused by adhesive processes, then a serious pathology can develop in the form of obstruction of the tubes and infertility. Then interventions are needed to correct this condition. Therefore, it is necessary to exclude such a cause of ovulatory disorders in time.
Diagnostics ovulatory syndrome
Diagnosis of ovulatory syndrome can be limited to anamnesis data only, but when the symptoms are intense, more serious research methods may be needed. First of all, it is necessary to find out from the woman whether these symptoms are the first time or they have bothered her before and the degree of their severity then and now. The reaction to antispasmodics or painkillers also plays an important role. If a woman says that after these drugs it becomes easier, then we are probably talking about functional disorders. It is also necessary to find out data on the duration of the menstrual cycle and the degree of severity of the pain syndrome. It is necessary to pay attention to what day of the cycle the pain syndrome occurs and if it is during the period of expected ovulation, then we can say that we are talking about ovulatory syndrome. And in most cases, further diagnostics are not necessary, at this stage you can decide on the treatment. But there are cases when it is impossible to associate the symptoms with ovulation with an irregular cycle. Then it is necessary to carry out clarifying research methods.
Tests aimed at diagnosing ovulatory pain syndrome are laboratory methods for confirming ovulation. The most reliable method is to determine the level of luteinizing hormone. The peak concentration of this hormone leads to the ovulation process, so its determination within certain numbers may indicate ovulatory syndrome. In this case, you can use simple quick tests based on the qualitative determination of this hormone, which can be purchased at a pharmacy. You can also use quantitative tests, but this analysis is more specific. If there is massive discharge during ovulatory syndrome, then there is a need to determine the level of estrogens and progesterone precisely during ovulation. In this case, a reduced amount of estrogens can cause similar symptoms and this must be taken into account when drawing up a treatment program.
Instrumental diagnostics of ovulatory pain syndrome should be carried out for the purpose of differentiation from other manifestations in complex manifestations of pathology. The main method that allows excluding serious pathology of the pelvic organs and abdominal cavity is ultrasound examination of the pelvis. In this case, it is possible to determine the presence of a cyst, apoplexy, free fluid in the parauterine space.
Differential diagnosis
Differential diagnostics of this syndrome during a severe pain attack must be carried out with diseases that give the clinical picture of an acute abdomen and require immediate surgical intervention.
When pain is localized on the right side of the lower abdomen, differential diagnostics with acute appendicitis should be performed. The distinctive feature of appendicitis is that the pain begins first in the epigastric region and then migrates to the right iliac region. Appendicitis is also accompanied by intoxication syndrome with an increase in temperature and a change in the blood test (a shift in the leukocyte formula to the left). Ovulatory pain is localized in the right iliac region from the very beginning and is not accompanied by symptoms of inflammation, in addition, the symptom of peritoneal irritation is not typical.
Ovarian apoplexy is a specific syndrome that occurs when there is bleeding into the ovary. Typical for this condition is, as a rule, a sharp nature of pain that occurs during physical activity or sexual intercourse. In this case, the ultrasound results can also determine free fluid in the pelvis and unclear echogenicity of the ovary.
Rupture of an ovarian cyst may be accompanied by sharp abdominal pain. At the same time, during the examination of a woman on the chair, pain is determined from the cyst and there is information about this disease in the anamnesis. Rupture of such a cyst is not associated with ovulation and can occur at any time of the cycle, which is what distinguishes ovulatory pain.
It is very important to differentiate ovulatory syndrome from ectopic pregnancy, which can also be accompanied by bloody vaginal discharge. But the main symptom can be considered a delay in menstruation when pregnancy is suspected and a normal menstrual cycle with ovulatory pain and corresponding discharge.
These are the main pathologies with which ovulatory pains must be differentiated in order to establish a diagnosis in time and, if necessary, not postpone surgical treatment. Anamnesis data is not always sufficient, so diagnostics must be comprehensive.
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Treatment ovulatory syndrome
Treatment of ovulatory syndrome is exclusively symptomatic if it is only a functional disorder. The use of hormonal drugs is possible only with a confirmed deficiency of certain hormones, which may be the cause of discharge during ovulatory syndrome. There are also folk methods of treating this pathology, which can be successfully used to reduce symptoms.
Of course, it is important during ovulation if a woman has this syndrome to limit physical activity, give preference to rest and normalize her diet by eating vegetables and fruits rich in vitamins and minerals.
The main medications are:
- Baralgin is a three-component drug that helps well with algomenorrhea and menstrual pain. The drug contains a non-narcotic analgesic (Metamizole sodium) and an antispasmodic (Pitofenone + Fenpiverinium bromide), which have a complex effect and relieve symptoms. Therefore, this drug is a symptomatic treatment drug. The drug is used for severe pain syndrome and is dosed one tablet. If the effect is not achieved, then after half an hour you can take another tablet. Precautions - do not take while breastfeeding and take for a long time, since it may have a depressing effect on hematopoiesis. Side effects are possible in the form of decreased blood pressure and allergic reactions.
- Tamipul is a complex remedy for symptomatic treatment of pain of any genesis, including ovulatory syndrome. It contains two non-narcotic analgesics (paracetamol and ibuprofen) and codeine. It has a central analgesic effect. The method of administration of the drug is oral. Dosage of one capsule for pain syndrome, better only at its onset, then the effect is more pronounced. Side effects are possible on the gastrointestinal tract in the form of glossitis, damage to the esophagus, stomach, intestines with dyspepsia, impaired evacuation function of the intestine. Also possible allergic reactions of varying severity. When the drug affects the hematopoietic system, anemia, a decrease in the number of platelets and granulocytic neutrophils may occur. When acting on the heart and vascular system, rapid heartbeat, pain in the heart, heart rhythm disturbances, lability of blood pressure may occur. Precautions - in case of severe pain syndrome, which is accompanied by severe intoxication syndrome, taking this drug can hide the clinical picture of acute abdomen, therefore the drug should not be used if another etiology of pain syndrome is suspected.
- Mirena is a contraceptive that can be used in the complex treatment of ovulatory pain that is intense and persistent. This drug, containing levonorgestrel, is the method of choice for women who have children and whose ovulation symptoms are accompanied by uterine discharge. At the same time, estrogen deficiency is regulated and the contraceptive effect is achieved at the same time. The method of using the drug is the insertion of an intrauterine device, which is carried out only by a specialized obstetrician-gynecologist. Such a device is installed for five years with subsequent replacement of the device. Precautions - minor preparation is required before using the intrauterine device. The mechanism of action of this drug is based on the effect of gradual release of estrogen hormones and normalization of discharge during ovulation.
- Perfectil is used for the complex treatment of ovulatory syndrome, since it has an effect not only on vitamin deficiency, but also on the regulation of nervous excitation in the case of a pronounced psychosomatic component of ovulatory syndrome. The drug contains vitamins - A, B1, B2, B5, B6, B9 B12, C, D, E, H, as well as trace elements - magnesium, calcium, copper, manganese, zinc, iron, molybdenum. The drug is available in the pharmacological form of capsules. Take one capsule once a day (preferably after meals, as this improves absorption). Side effects are not detected if the dose is observed, changes in urine color are possible due to the composition of the drug. Contraindications to taking the drug are serious kidney and liver dysfunction. Precautions - do not combine with other vitamins.
Physiotherapy treatment has a positive effect in the acute period, especially when adhesions form on the ovaries. In the acute period, heat can be applied to the lower abdomen, as well as radiation therapy. If there is a suspicion of an acute inflammatory process, then thermal procedures are strictly contraindicated.
Surgical treatment of ovulatory symptoms is not used; only some surgical manipulations are possible in the case of tubal adhesions and obstruction.
Traditional treatment of ovulatory syndrome
Traditional methods of treatment are also aimed at eliminating pain syndrome and normalizing the emotional state. They use methods that eliminate spasms and have an analgesic effect.
- A salt heating pad dilates spasmodic blood vessels and relaxes muscles, which reduces the intensity of ovulatory pain. To make such a heating pad, heat the salt in a frying pan until it is warm, pour it into a towel, fold it in several layers so that it is not hot, and then apply it to the lower abdomen. If there is any increase in temperature, no heating pads should be used.
- You need to make a sitz bath from chamomile and cinnamon infusion. To do this, brew two bags of chamomile in a liter of water and let it sit until the solution becomes warm. Then you need to add a teaspoon of cinnamon and take such a bath, sitting in it for at least ten minutes.
- Before the expected ovulation, you need to use a tampon made of calendula herb. It has an antimicrobial and analgesic effect. To do this, you need to brew calendula flowers and wet a gauze tampon, insert it into the vagina for two hours.
Herbal treatment can be used for several days, using medicinal herbs for two days before the expected ovulation and two days after it. This also normalizes the nervous system and blood circulation.
- Celery is a plant that is not only eaten, but also used to reduce pain. The root of this plant is poured with cold water, the juice of half a lemon is added and half a glass of this drink is drunk three times a day. It also normalizes the amount of missing hormones.
- One tablespoon of horsetail should be mixed with several sprigs of lemon balm and poured with hot water. This infusion should be drunk three tablespoons at a time, warm.
- A combination of orthilia secunda and wild strawberry regulates bloody discharge during ovulatory syndrome. To do this, take the leaves of the orthilia secunda and add a tablespoon of fruits or strawberry leaves. This infusion can be drunk as tea three times a day, one glass at a time.
- Water pepper and nettle leaves can be used if ovulatory syndrome is combined with heavy discharge, which indicates a sharp deficiency of gestagens. For this, use an infusion of these herbs and drink half a glass twice a day.
Homeopathic remedies have the same principle of action as other drugs, that is, symptomatic treatment is used. Also, treatment can have a preventive nature in the correction of the formation of adhesions on the ovary.
- Lachesis Plus is a combined homeopathic remedy that affects all disorders of the body's regulatory processes, and due to its rich herbal composition, has an analgesic and antispasmodic effect. The drug is available in the pharmacological form of homeopathic granules and is dosed eight granules five times a day half an hour before meals or an hour after. It is necessary to dissolve the granules until completely dissolved and not to drink water. Side effects are rare. Perhaps a slight increase in abdominal pain, then it is necessary to increase the dose to five drops. Treatment should be carried out for at least two months, and for the purpose of prevention, reduce the dose and take five granules three times a day.
- Ignatia Homaccord is a complex herbal and animal homeopathic remedy that is especially effective in cases of psychosomatic disorders that accompany ovulatory pain. The drug is available in the pharmacological form of homeopathic drops and is dosed ten drops once a day. In this case, the drops should be diluted in a tablespoon of water and taken regardless of food intake. No side effects have been identified.
- Pulsatilla compositum is a homeopathic remedy of natural origin. The drug is produced in the pharmacological form of a homeopathic solution in ampoules and is dosed in a third of an ampoule once a week with possible oral use. Side effects are rare, but stool disorders, dyspeptic phenomena and allergic reactions may occur. Precautions - the drug cannot be used in acute uterine processes.
- Belladonna is a single-component drug that has a very pronounced antispasmodic effect due to blocking cholinergic receptors in muscle fibers. The method of administration of the drug is one tablet once a day. Side effects are possible with an overdose of the drug, so you need to follow the doctor's instructions.
These are the main folk remedies, the advantage of which is the possibility of their preventive use.
Prevention
Prevention of any ovulation disorders is non-specific methods. It is necessary to observe the rules of personal hygiene, intimate hygiene with regular sexual relations, which helps to normalize the hormonal background. It is also necessary to prevent inflammatory diseases of the ovaries and timely treat various pathologies.
Forecast
The prognosis for ovulatory syndrome is favorable in any case, since it is a functional disorder that is easily corrected.
Ovulatory syndrome is one of the common complaints of women of reproductive age, which disrupts daily activity and is accompanied by recurring painful sensations caused by ovulation. It is not a pathological condition, but with any changes in pain syndrome or the appearance of other symptoms, it is necessary to consult a doctor for differential diagnostics. Treatment of this pathology is symptomatic and does not require special medical prescriptions, so you can take painkillers, but only if you are sure of the cause.