Maxamine forte

Maxamin Forte is a multivitamin complex containing useful microelements. It is used in case of development of microelement deficiency with vitamins in the body (during lactation or convalescence, and also as an additional means in treatment with antibiotics). The medicine gives good results in treatment of pigmentary dystrophy of the retina, dry eye syndrome, and also night blindness, xerous keratitis, diseases and injuries of the epithelium with skin and eczematous lesions of the eyelids.

Indications Maxamine forte

Among the indications:

• avitaminosis or hypovitaminosis;
• inadequate, incorrect diet;
• increased stress (both physical and mental);
• rehabilitation period after illnesses;

Post-surgical period.

Release form

It is produced in the form of tablets. One strip contains 10 tablets. The strip is placed in a paper envelope. The package contains 10 such envelopes.

Pharmacodynamics

Vitamin D stimulates the absorption of phosphorus and calcium from the intestines. In addition, it helps form healthy bones and teeth and promotes their functioning.

Water-soluble vitamins from group B (such as riboflavin, thiamine, and also cyanocobalamin and pyridoxine) improve metabolic processes and are also components of other compounds (for example, coenzymes). They influence the metabolism of proteins, as well as carbohydrates with amino acids, and also the synthesis of DNA and other molecules. Along with this, they participate in the process of formation of red blood cells, as well as the functioning of nerve cells during oxidation-reduction reactions.

Vitamin (water-soluble) of group C is an important component in the regulation of oxidation-reduction processes of carbohydrate metabolism, tissue healing and blood clotting. It also takes part in the processes of collagen and corticosteroid synthesis. Vitamin C regulates capillary permeability, improves immunity, and has an antioxidant effect.

Nicotinic acid is a water-soluble vitamin that has specific anti-pellagra properties, and in addition, it helps improve carbohydrate metabolism. It also improves the condition of patients suffering from heart and liver diseases, mild diabetes, duodenal or gastric ulcers, long-healing wounds and enterocolitis. It also has a vasodilatory effect. This component has hypolipidemic activity, lowers the concentration of cholesterol and low-density lipoproteins (especially triglycerides).

Vitamin B9 promotes the correct formation of megaloblasts with subsequent formation of erythroblasts. It also affects erythropoiesis and the synthesis of various substances - amino acids (such as serine, methionine, etc.), purines, nucleic acids, and pyrimidines.

Pantothenic acid is a water-soluble vitamin and is part of coenzyme A, which participates in oxidation processes and acetylation. In addition, it helps fat and carbohydrate metabolism, the process of acetylcholine synthesis and the formation of corticosteroids. It is used to eliminate diseases that arise due to metabolic disorders. In neuralgic pathologies, polyneuritis, allergies, paresthesia, the development of eczema, burns and trophic ulcers, as well as in gastrointestinal diseases (of non-infectious origin) and toxicosis in pregnant women. It enhances the medicinal effect of cardiac glycosides, and also reduces the toxicity of anti-tuberculosis drugs.

Tocopherol acetate is a natural fat-soluble antioxidant that takes part in the biosynthesis of proteins and heme. In addition, it also takes part in cell reproduction, tissue respiration and other important metabolic processes in cells. It is used for muscle dystrophy.

Iron is an important component in the process of transporting electrons and oxygen through the body's tissues. Calcium helps form bone tissue and is also involved in the process of hemostasis. Copper is one of the components in the enzyme system (cofactor) when using iron during hemoglobin synthesis.

Zinc is an essential micronutrient that is usually obtained through diet. It is part of many enzymes and insulin. Magnesium acts as a metabolic activator. It is needed by some enzymes to perform at their maximum potential (such as phosphatases and peptidases). Manganese sulfate is involved in fat metabolism, helps form the structure of bone and connective tissue, and produces cholesterol.

Pharmacokinetics

Retinol is a fat-soluble vitamin and is quickly absorbed through the upper small intestine, penetrating the liver. After taking the drug, the substance reaches peak concentration in the blood plasma after 4 hours. Distribution in the body is uneven - retinol is mainly concentrated in the retina and liver. Decay products are excreted with urine. The half-life is 9.1 hours. In a healthy person, unmetabolized vitamin is not detected in the urine, since it is excreted with bile.

Cholecalciferol is also a fat-soluble substance that is absorbed from the small intestine. The substance accumulates in the liver and is excreted mainly with bile. Excess ascorbic acid remains unchanged and is excreted with urine.

Folic acid is a water-soluble component. It is restored in the body, transforming into tetrahydrofolic acid (a coenzyme that takes part in various metabolic processes).

Dosing and administration

Tablets should be taken orally with food (ideally at breakfast), with water and without chewing. For children 12+ years old and adults, the dosage is 1 tablet per day (unless otherwise prescribed by a doctor).

Use Maxamine forte during pregnancy

High doses of retinol during pregnancy have been associated with teratogenic effects. Therefore, the drug should not be prescribed in early pregnancy.

Contraindications

Among the contraindications:

• the presence of individual intolerance to the elements of the drug;
• renal failure;
• existing hypervitaminosis type A or D;
• hypercalcemia;
• combination with other medications that contain vitamins A or D;
• treatment course using systemic retinoids;
• children under 12 years of age.

Side effects Maxamine forte

Side effects of the drug include allergies in the form of hives and itchy skin.

Overdose

Overdosing on vitamin A can cause diarrhea, headaches, vision problems, bone pain, anorexia or gastralgia. In addition, baldness, increased fatigue, anemia or hepatosplenomegaly, vomiting, subperiosteal hemorrhage and premature fusion of the bone epiphysis.

As a therapy, it is necessary to stop taking the medication and eliminate the symptoms that have arisen.

Overdose of vitamin D may cause vomiting, headaches, thirst, and also polyuria, soft tissue calcification, urolithiasis, or nephrocalcinosis.

Treatment: Stop taking the medication and start following a diet (low calcium intake and drinking plenty of electrolytes with liquids).

Overdose of vitamin B6: development of ataxia or peripheral neuropathy. Excess iron can cause vomiting with nausea, as well as the development of erosive and ulcerative processes in the gastrointestinal tract.

As a therapy, it is necessary to induce vomiting and then wash out the stomach. Deferoxamine is also prescribed and treatment of the symptoms that have arisen is carried out.

Interactions with other drugs

As a result of the combination of Maxamin Forte with contraceptives containing estrogen, the properties of retinol are enhanced.

As a result of combining the drug with tetracyclines, intestinal absorption of retinol increases and its level in tissues and the liver increases.

The combination of the drug with cholestyramine slows down the rate of absorption of retinol with cholecalciferol.

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Storage conditions

Maxamin Forte should be kept in standard conditions - a dry, dark place, out of reach of children. The temperature should be maintained within 15-25°C.

Shelf life

Maxamin Forte is permitted to be used for 2 years from the date of manufacture of the medicine.