Hepabene

Gepabene has choleretic and hepatoprotective activity.

[ 1 ], [ 2 ]

Indications Hepabene

It is used for the following diseases:

• having a chronic form of toxic disease affecting the liver;
• chronic hepatitis;
• dysfunction of the biliary tract (this includes conditions that develop as a result of the cholecystectomy procedure ), in combination with other medications used for such disorders.

[ 3 ]

Release form

The therapeutic drug is released in capsules, 30 pieces per pack.

Pharmacodynamics

Gepabene is a complex herbal medicine that includes extracts made from milk thistle and wild rue, whose properties provide its therapeutic effect. The drug is used to stabilize liver function in various pathologies.

Wild rue, which contains fumarin alkaloid, helps to stabilize the amount of bile secreted, thereby facilitating its flow into the intestinal area, and also eliminates spasms of the gallbladder and bile ducts.

Silymarin, which is a component of milk thistle, has a hepatoprotective effect, developing in the case of liver poisoning, which has an acute or chronic form (synthesizing toxic elements with free radicals inside the liver tissue). In addition, it stimulates protein binding processes, has an antioxidant and membrane-stabilizing effect, and also helps restore damaged liver cells.

Pharmacokinetics

After oral administration, silymarin flavonoids undergo recirculation processes in the intestinal and hepatic regions. Excretion occurs mainly with bile.

Dosing and administration

The therapeutic cycle scheme is selected for each patient individually. The capsules should be taken with food, without crushing or chewing them (swallow with plain water).

Usually, 3 capsules are required per day (at approximately equal time intervals). If pain occurs at night, an additional capsule may be taken before bedtime. The daily dose may be increased to 6 pieces (this dosage is maximum), which are taken 3-4 times per day.

[ 4 ]

Use Hepabene during pregnancy

The question of using the medication during lactation or pregnancy should be decided by the patient's attending physician.

Contraindications

Among the contraindications:

• the presence of intolerance to the components of the capsules;
• acute diseases affecting the liver and biliary tract (in the acute stage).

Side effects Hepabene

Sometimes taking capsules leads to increased diuresis, various allergy symptoms and a laxative effect.

Overdose

There is currently no information on poisoning with Gepabene. If a patient accidentally takes too many capsules, they should consult their doctor.

Storage conditions

Hepabene is usually kept at standard temperatures of maximum 25°C.

[ 5 ]

Shelf life

Gepabene can be used for a period of 5 years from the date of manufacture of the pharmaceutical product.

Application for children

Gepabene is prohibited for use in pediatrics.

[ 6 ]

Analogues

The following substances are analogs of the drug: Allochol, Convaflavin, Holosas with Flamin, Cholagol with Tsikvalon, and in addition, artichoke extract, Olimetin, Choleretic collection No. 3, Hofitol with Leptandra Compositum, Liobil with Odeston, Kavehol, tansy flowers and Fitogepatol.

Reviews

Gepabene usually receives good reviews from medical professionals – it demonstrates high efficiency in pain associated with the gallbladder and liver.

Comments left on medical forums by patients who have used the medication in combination with other means used in such cases are almost always positive. Only occasionally is the development of negative symptoms noted (pain or a feeling of heaviness in the right hypochondrium, diarrhea and a feeling of weakness), which is not considered a serious drawback of the medication.