Gripmax Nose

Gripmaks Nose is a natural complex preparation designed to relieve cold and flu symptoms and to support the respiratory system. This preparation contains a wide range of plant extracts and other natural components, each of which has specific medicinal properties:

1. Bromelain (from Ananas comosus) is an enzyme obtained from the stems and juice of pineapples. It has anti-inflammatory and mucolytic effects, helps to thin mucus and facilitate its discharge.
2. Thyme herb extract (Thymus serpyllum) - known for its antiseptic and antimicrobial properties, helps with coughs and inflammation of the upper respiratory tract.
3. Ivy leaf extract (Hedera helix L.) - used to treat coughs and as a mucolytic agent, helps reduce the viscosity of sputum and facilitate breathing.
4. Mallow flower extract (Malva sylvestris L.) - has enveloping and softening properties, helps with irritation of the mucous membranes.
5. Echinacea purpurea L. Moench. herb extract - stimulates the immune system, has anti-inflammatory properties, helps fight viral and bacterial infections.
6. Eucalyptus viminalis Labill. leaf extract - contains eucalyptus oil, which helps clear the respiratory tract, has antibacterial and antiseptic properties.
7. L-ascorbic acid (vitamin C) - supports the immune system, helps reduce the duration and severity of colds.

This medicine is intended for use at the first symptoms of colds and flu, such as cough, runny nose, sore throat and difficulty breathing. It helps reduce inflammation, make breathing easier and speed up the healing process.

Indications Gripmax Nose

1. Runny nose and nasal congestion: The herbal extracts of thyme, ivy, mallow and eucalyptus leaves contained in Gripmax Nose can help relieve nasal congestion and ease breathing.
2. Colds and Flu: This medication can be used to reduce symptoms of colds and flu, such as fever, headache, muscle aches and weakness.
3. Strengthening the immune system: Echinacea purpurea (coneflower) herb extract and vitamin C may help strengthen the immune system and make the body more resistant to infections.
4. Cold and Flu Prevention: Gripaks Nose can also be used as a preventative to reduce the risk of contracting cold and flu viruses.

Release form

Gripmaks Nose is usually available in tablet form.

Pharmacodynamics

1. Bromelain (from Ananas comosus): Bromelain is a proteolytic enzyme that has anti-inflammatory and mucolytic properties. It is able to break down the mucopolysaccharides in mucus, which helps to thin the mucus and make it easier to cough up.
2. Creeping Thyme Herb Extract (Thymus serpyllum): Creeping Thyme has anti-inflammatory, antiseptic, and mucolytic properties. It helps reduce inflammation in the respiratory tract and facilitate expectoration.
3. Ivy leaf extract (Hedera helix L.): Ivy has a mucolytic and expectorant effect, helping to thin and remove mucus from the respiratory tract.
4. Mallow (Malva sylvestris L.) flower extract: Used as a mild demulcent to soothe throat irritation and relieve coughs.
5. Echinacea purpurea L. Moench. herb extract: Echinacea has immunomodulatory properties and helps strengthen the body's immune system.
6. Eucalyptus viminalis Labill. Leaf Extract: Eucalyptus has anti-inflammatory and expectorant properties, helping to reduce inflammation and facilitate expectoration.
7. L-ascorbic acid (vitamin C): Vitamin C strengthens the immune system and helps the body fight viral infections such as colds and flu.

Pharmacokinetics

1. Bromelain: Bromelain is generally rapidly absorbed from the gastrointestinal tract. Its metabolism occurs primarily in the liver. It may enhance the absorption of some drugs by increasing their bioavailability.
2. Herbal extracts: Depending on the dosage form (e.g. drops, spray), herbal extracts can be absorbed through the nasal mucosa and respiratory tract. Their pharmacokinetics may vary depending on the route of administration.
3. Vitamin C (L-ascorbic acid): Vitamin C is generally well absorbed from the gastrointestinal tract and is rapidly metabolized in the body. Its excretion occurs primarily through the kidneys.

Dosing and administration

1. Directions for use:

   • Shake bottle well before use.
   • Tilt your head forward slightly and insert the end of the bottle into your nostril.
   • Press the bottle to spray the product into your nose.
   • Inhale with light, deep breaths through your nose while diffusing.

2. Dosage:

   • It is generally recommended to apply 1-2 sprays into each nostril.
   • The frequency of use may vary depending on individual needs and your doctor's recommendations. Typically, it is no more than 2-3 times a day.

3. Notes:

   • It is important not to exceed the recommended dosage or use the drug for longer than recommended.
   • If you have any questions or concerns regarding the use of Gripmaks Nos, be sure to consult your doctor or pharmacist.

Use Gripmax Nose during pregnancy

There may be limited safety information about using Gripmax Nose during pregnancy. Before using this medication during pregnancy, it is important to consult with your doctor or obstetrician-gynecologist. They will be able to assess the risks and benefits of using it in your case and give recommendations based on your health and pregnancy status. The components of the drug, such as bromelain, thyme extract, ivy extract, mallow extract, echinacea extract, eucalyptus extract and L-ascorbic acid, may have different effects on the body during pregnancy, so it is important to get advice from a qualified healthcare professional.

Contraindications

1. Bromelain (from Ananas comosus):

   • Not recommended for people with known allergies to pineapple or other bromeliads.
   • There may be restrictions on use in people with gastric ulcer or duodenal ulcer.

2. Creeping Thyme Herb Extract (Thymus serpyllum):

   • Thyme is generally considered safe, but people with allergies to plants in the Lamiaceae (mint) family may experience an allergic reaction.

3. Ivy leaf extract (Hedera helix L.):

   • Ivy may cause an allergic reaction in some people.
   • Not recommended for use by pregnant or lactating women without consulting a doctor.

4. Mallow flower extract (Malva sylvestris L.):

   • Generally well tolerated, but some people may experience an allergic reaction.

5. Echinacea purpurea L. Moench herb extract:

   • May cause allergic reactions in people with allergies to plants of the Asteraceae family.

6. Eucalyptus viminalis Labill. leaf extract:

   • Eucalyptus may cause an allergic reaction in some people.
   • Not recommended for use in children under 6 years of age without consulting a doctor.

7. L-ascorbic acid (vitamin C):

   • Contraindications are limited. However, taking large doses of vitamin C may cause stomach upset.

Side effects Gripmax Nose

1. Bromelain (from Ananas comosus):

   • May cause allergic reactions in individuals with pineapple allergies.
   • In rare cases, it may cause gastrointestinal disturbances such as diarrhea or stomach discomfort.

2. Creeping Thyme Herb Extract (Thymus serpyllum):

   • Due to its antiseptic properties, it may cause irritation of the mucous membranes in some people.

3. Ivy leaf extract (Hedera helix L.):

   • May cause skin reactions or irritation upon contact with skin or mucous membranes.
   • In rare cases, it may cause breathing problems, especially in people with asthma.

4. Mallow flower extract (Malva sylvestris L.):

   • Generally well tolerated, but may cause allergic reactions in sensitive individuals.

5. Echinacea purpurea L. Moench herb extract:

   • May cause allergic reactions, especially in people allergic to other plants of the Asteraceae family.
   • Long-term use is not recommended as it may reduce the effectiveness of the immune system with prolonged use.

6. Eucalyptus viminalis Labill. leaf extract:

   • May cause irritation to throat or respiratory tract, especially if oil is inhaled in large quantities.

7. L-ascorbic acid (vitamin C):

   • In normal doses it is well tolerated, but in high doses it may cause stomach upset, diarrhea or kidney stones.

Overdose

1. Bromelain: Overdosing on bromelain may cause diarrhea, nausea, vomiting, allergic reactions, or increased inflammation in the mouth.
2. Creeping Thyme Herb Extract: Side effects such as allergic reactions or diarrhea may occur.
3. Ivy Leaf Extract: Overdosing on ivy may result in rare side effects such as nausea, vomiting, diarrhea, or allergic reactions.
4. Mallow Flower Extract: Overdose may cause drowsiness, dizziness, or gastrointestinal upset.
5. Echinacea Purpurea Herb Extract: May cause allergic reactions or gastrointestinal upset.
6. Eucalyptus Vitula Leaf Extract: Overdose may cause nausea, vomiting, diarrhea, or allergic reactions.
7. L-ascorbic acid (vitamin C): Overdosing on vitamin C can lead to diarrhea, gastrointestinal upset, vomiting, allergic reactions, or even kidney stones in people with high levels of oxalates in their urine.

Interactions with other drugs

1. Ascorbic acid (vitamin C):

   • Interaction with aspirin (acetylsalicylic acid): Vitamin C may increase the elimination of aspirin from the body and reduce its effectiveness.
   • Interaction with amphetamines: Vitamin C can increase the acidity of urine, which reduces the absorption of amphetamines and increases their elimination from the body.
   • Interaction with aluminum, iron and zinc: Vitamin C can increase their absorption in the gastrointestinal tract.

2. Echinacea Purpurea Herb Extract:

   • Interaction with immunosuppressive drugs: Echinacea may enhance the immune response and decrease the effectiveness of immunosuppressive drugs.

3. Eucalyptus Vitula Leaf Extract:

   • Interaction with blood sugar lowering medications: Eucalyptus may increase blood sugar levels and reduce the effectiveness of blood sugar lowering medications.

4. Ivy leaf extract:

   • Interaction with anticoagulants: Ivy may enhance the effect of anticoagulants and increase the risk of bleeding.

5. Creeping Thyme Herb Extract:

   • Interaction with sedatives: Thyme may enhance the sedative effects of some medications, such as benzodiazepines.

6. Mallow flower extract:

   • Interaction with antihypertensive drugs: The use of mallow can enhance the hypotensive effect of antihypertensive drugs, which can lead to excessive reduction in blood pressure.

7. Bromelain (from Ananas comosus):

   • Interaction with anticoagulants: Bromelain may enhance the effect of anticoagulants and increase the risk of bleeding.