Gorpils

Gorpils is a combination drug containing two active ingredients: amylmetacresol and 2,4-dichlorobenzyl alcohol. It is commonly used as an antimicrobial agent to treat and prevent infections in the throat and mouth. These substances have antiseptic properties and can help fight bacteria and fungi that cause infections. Gorpils is available as a spray or gargle.

Indications Gorpils

1. Throat diseases such as tonsillitis, pharyngitis, laryngitis.
2. Oral diseases such as stomatitis.
3. Prevention of infections after surgical interventions in the throat or oral cavity.
4. Symptomatic treatment of pain and irritation in the throat associated with infectious processes.

Release form

Gorpils is available in the form of lozenges or tablets for resorption, which ensures a gradual release of active ingredients upon contact with the mucous membrane of the throat.

Pharmacodynamics

1. Antimicrobial action: Amylmetacresol and 2,4-dichlorobenzyl alcohol have antimicrobial action against a wide range of microorganisms, including bacteria, fungi and viruses. They help destroy and inhibit the growth of pathogenic microorganisms, which helps to quickly relieve the symptoms of throat infections.
2. Anti-inflammatory action: Gorpils can also have an anti-inflammatory effect, reducing inflammation in the throat and mouth. This helps reduce pain, irritation and redness of the mucous membranes.
3. Analgesic effect: The drug may have a mild analgesic effect, which helps reduce pain and discomfort when swallowing or other movements in the throat.
4. Local anesthetic effect: It is possible that amylmetacresol and 2,4-dichlorobenzyl alcohol also have a local anesthetic effect by blocking nerve impulses and decreasing the sensitivity of pain receptors in the throat and mouth.
5. Improving conditions for healing: Due to its antiseptic properties, the drug can help create favorable conditions for tissue healing, accelerating the recovery process from throat and oral infections.

Pharmacokinetics

The pharmacokinetics of Gorpils, which contains amylmetacresol and 2,4-dichlorobenzyl alcohol, are generally not as well studied as the pharmacokinetics of the individual active ingredients. However, in general, the pharmacokinetics of these components can be roughly described as follows:

1. Amylmetacresol: It is an antiseptic agent that is commonly used to combat infections in the throat and mouth. After application in the form of a drug, it can be absorbed into the mucous membrane of the throat and mouth and gradually released.
2. 2,4-Dichlorobenzyl Alcohol: This is another antiseptic often used to treat throat infections. After application, it can also be absorbed into the mucous membrane of the throat and mouth and gradually released.

In both cases, the metabolism and excretion of these compounds usually occur through metabolic processes in the body or their excretion in the urine.

Dosing and administration

It is recommended to dissolve 1-2 lozenges every 2-3 hours for adults and children over 6 years of age.

Use Gorpils during pregnancy

The use of any medications, including Gorpils, during pregnancy should only be done after consultation with a doctor. Although many medications are considered safe for use during pregnancy, it is always best to get advice from a doctor to ensure that they are safe for you and your baby.

Gorpils is a combination drug containing antiseptics (amylmetacresol and 2,4-dichlorobenzyl alcohol) and anesthetic lidocaine. It is important to consider that even if some components of the drug can be considered safe, the combination with other ingredients may affect its safety during pregnancy.

Contraindications

1. Hypersensitivity or allergic reaction: People with a known allergy to amylmetacresol, 2,4-dichlorobenzyl alcohol or other components of the drug should avoid using it.
2. Children under 6 years: Some forms of Gorpils are not recommended for use in children under 6 years of age without a doctor's advice.
3. Pregnancy and breastfeeding: If you are pregnant or breastfeeding, you should consult your doctor before using Gorpils to ensure it is safe.
4. Long-term use: Do not use Gorpils for a long time without the advice of a doctor, as this may lead to the development of resistance to the drug or other problems.
5. Use in patients with thyroid disease: Caution should be exercised in patients with thyroid disease, as amylmetacresol may affect thyroid function.

Side effects Gorpils

1. Rare hypersensitivity or allergic reactions such as itching, skin rash, swelling of the larynx or face.
2. Rarely, a burning, tingling, or other unpleasant sensation in the throat or mouth may occur after using the drug.
3. An unpleasant aftertaste may occur after the tablet has dissolved.

Overdose

An overdose of any medication can be dangerous and requires immediate medical attention. If you suspect an overdose of Gorpils (amylmetacresol, 2,4-dichlorobenzyl alcohol), it is important to seek immediate medical attention.

Overdose symptoms may include nausea, vomiting, dizziness, weakness, confusion, and other unpleasant sensations.

Interactions with other drugs

1. Other antimicrobials: When used together with other antimicrobials, especially topical ones, their effects may be enhanced or weakened due to possible competitive action or interaction at the level of adsorption.
2. Systemic antiseptics and antibiotics: Although Gorpils is applied topically, in some cases systemic effects may occur due to absorption of its components into the bloodstream through the mucous membrane. In such cases, it is important to be careful when using systemic antiseptics and antibiotics to prevent possible adverse interactions.
3. Other topical medicinal products: When using Gorpils simultaneously with other topical medicinal products for the treatment of throat or oral infections, the possibility of interaction or competitive action between the active ingredients should be taken into account.
4. Drugs that reduce stomach acidity: This may be important when using formulations of Gorpils that dissolve or are absorbed into the mucosa, as changes in acidity may affect their effectiveness.