Dysflatil

Disflatil contains the active ingredient simethicone, which is a substance used to relieve excess gas in the stomach and intestines by reducing the surface tension of gas bubbles. This allows the gas to combine into larger bubbles, making it easier for it to leave the body through the digestive system.

Simethicone is a polymeric silicone that is not absorbed into the body and has no systemic effects. It simply facilitates the release of gas from the digestive tract, reducing the discomfort associated with excess gas, such as bloating, colic, pressure, and abdominal discomfort.

Disflatil is commonly used for the symptomatic treatment of bloating and excess gas that may occur after eating or as a result of certain medical conditions such as irritable bowel syndrome.

Indications Dysfunctional

1. Excessive Gas: The product helps reduce and facilitate the removal of gases from the digestive tract, which can lead to a reduction in bloating, discomfort and pain in the abdomen caused by excess gas.
2. Bloating: Disflatil can be used to relieve feelings of tension and pressure in the abdomen caused by gas build-up in the intestines.
3. Colic: The drug may help relieve the symptoms of intestinal colic caused by gas, especially in infants and young children.
4. Other symptoms of excess gas include: A feeling of fullness in the abdomen, frequent gas, or bloating after eating.

Release form

Disflatil usually comes as a liquid or drops.

Pharmacodynamics

1. Reducing Surface Tension: Simethicone works by reducing the surface tension of gases, causing large gas bubbles to break up into smaller, more easily removed bubbles. This allows gases to dissipate more effectively and pass out of the stomach and intestines through the mouth or rectum.
2. Discomfort relief: By reducing the volume and pressure of gases in the stomach and intestines, simethicone can help reduce discomfort, bloating, bloating, and pain associated with excess gas.

Pharmacokinetics

The pharmacokinetics of simethicone are generally characterized by the absence of systemic absorption, metabolism and elimination from the body. This means that simethicone is not absorbed into the blood from the gastrointestinal tract, is not metabolized in the body and is excreted unchanged.

Dosing and administration

1. Directions for use:

   • Disflatil is usually taken after meals or when discomfort due to gas occurs.
   • If it is presented as a liquid, the dose can be measured using a measuring cup or spoon, which are usually supplied with the drug.
   • If it comes in drops form, they can be taken directly or added to water or other liquid before drinking.

2. Dosage:

   • The dosage of Disflatil usually depends on the individual patient's needs and the degree of discomfort.
   • The usual dosage for simethicone is 40-360 mg per dose, up to 4 times daily.
   • For exact dosage and recommendations, please refer to the instructions for use or consult your doctor or pharmacist.

Use Dysfunctional during pregnancy

The use of Disflatil during pregnancy is considered safe. Simethicone is widely used to reduce gas and bloating because it acts locally in the gastrointestinal tract and is not absorbed into the systemic circulation.

1. In a review of the use of over-the-counter drugs during pregnancy, simethicone was mentioned as one of the agents that can be safely used by pregnant women to treat bloating and abdominal discomfort caused by gas (Werler et al., 2005).
2. A study using simethicone in combination with metoclopramide after cesarean section showed that its use can reduce opioid requirements and speed up recovery time after surgery, further supporting its safety and potential benefit when used in the perioperative period in pregnant women (Martingano et al., 2019).

It should be noted that despite its widespread use and lack of systemic absorption, consultation with a physician before starting any therapy during pregnancy is always recommended. This will help ensure safety for both the mother and the developing fetus.

Contraindications

1. Hypersensitivity: People with known hypersensitivity to simethicone or other components of the drug should avoid its use.
2. Severe intestinal disorders: In case of severe intestinal disorders such as intestinal obstruction or peritonitis, the use of Disflatil is not recommended without consulting a doctor.
3. Pregnancy and Breastfeeding: Although simethicone is generally considered safe during pregnancy and breastfeeding, it is important to discuss use with your doctor for specific recommendations.
4. Paediatric population: Use of Disflatil in children is recommended with caution and in accordance with the doctor's instructions or the directions on the package.
5. Use in severe cases: If you experience severe symptoms such as severe abdominal pain, vomiting, blood in the stool or other unusual symptoms, you should seek medical attention and not just rely on self-medication with simethicone.
6. Use with other medications: In case of using other medications, especially taking medications with other drug interactions, it is always better to discuss the use of Disflatil with your doctor.

Side effects Dysfunctional

1. Allergic reactions: In some cases, allergic reactions such as skin rash, itching or even anaphylaxis may occur, although such cases are extremely rare (Tongprasert et al., 2009).
2. Gastrointestinal symptoms: In rare cases, simethicone may cause mild gastrointestinal symptoms such as nausea or abdominal discomfort (Jia Ling-zh, 2015).
3. No effect on certain conditions: In studies evaluating the effectiveness of simethicone in treating colic in infants, it was found to be ineffective compared to placebo. This suggests that simethicone may not be effective for all types of gastrointestinal problems (Metcalf et al., 1994).

Overdose

Overdose of simethicone contained in Disflatil is usually rare due to its low toxicity and lack of systemic side effects during normal use. However, in case of overdose, some unpleasant symptoms such as excess gas or bloating may occur.

Because simethicone is not absorbed into the bloodstream and does not have systemic effects, serious complications from overdose are unlikely. In most cases, overdose symptoms will be temporary and may include increased symptoms of excess gas or temporary increased stomach or intestinal discomfort.

Interactions with other drugs

Simethicone, the main component of Disflatil, is generally considered safe and does not interact with other medications. Because simethicone is not absorbed into the body and does not interact with the pharmacological mechanisms of other drugs, the likelihood of it interacting with other drugs or supplements is extremely low.

Storage conditions

1. Temperature: Store this medicine at room temperature, usually between 15°C and 30°C (59°F and 86°F). Avoid storing in places with extreme temperatures and avoid freezing the medicine.
2. Packaging: Before use, make sure that the packaging of the drug is intact. If the packaging is damaged or expired, the drug should be disposed of in accordance with local rules and regulations.
3. Child safety: Keep Disflatil out of reach of children to prevent accidental ingestion.