Diseases of the blood (hematology)

Multiple myeloma

Multiple myeloma (myelomatosis; plasma cell myeloma) is a plasma cell tumor that produces a monoclonal immunoglobulin that implants and destroys nearby bones.

Monoclonal gammopathy of undetermined nature

With monoclonal gammopathy of an indeterminate nature, M-protein is produced by non-malignant plasma cells in the absence of other manifestations of multiple myeloma. The incidence of monoclonal gammapathy of uncertain character (MGNH) increases with age, from 1% in people aged 25 to 4% in people older than 70 years.

Macroglobulinemia

Macroglobulinemia (primary macroglobulinemia, Waldenstrom's macroglobulinemia) is a malignant plasma-cell disease in which B cells produce large amounts of monoclonal IgM. Manifestations of the disease include increased blood viscosity, bleeding, recurrent infections and generalized adenopathy.

Diseases of heavy chains: causes, symptoms, diagnosis, treatment

Diseases of heavy chains are neoplastic plasma-cell diseases characterized by hyperproduction of heavy chains of monoclonal immunoglobulin. Symptoms, diagnosis and treatment vary according to the specificity of the disease.

Plasma cell diseases: causes, symptoms, diagnosis, treatment

Plasma cell diseases (dysproteinemia, monoclonal gammopathies, paraproteinemia, plasma cell discourses) are a group of diseases of unknown etiology characterized by a disproportional proliferation of one B cell clone, the presence of structurally and electrophoretically homogeneous (monoclinic) immunoglobulins or polypeptides in blood serum or urine.

Mushroom Mycosis: Causes, Symptoms, Diagnosis, Treatment

Mushroom mycosis is less common than Hodgkin's lymphoma and other types of non-Hodgkin's lymphomas. Mushroom mycosis has a latent origin, often manifesting as a chronic itchy rash, difficult to diagnose. Starting locally, it can spread, affecting most of the skin. Places of damage are similar to plaques, but can manifest as nodules or sores. Subsequently, systemic damage to the lymph nodes, liver, spleen, lungs develops, systemic clinical manifestations are added that include fever, night sweats, unexplained weight loss.

Burkitt's lymphoma: causes, symptoms, diagnosis, treatment

Burkitt's lymphoma is B-cell lymphoma, found predominantly in women. There are forms of endemic (African), sporadic (non-African) and associated with immunodeficiency. Burkitt's lymphoma is endemic in central Africa and accounts for up to 30% of children's lymphomas in the United States. Endemic for Africa manifests itself in the form of lesions of facial bones, jaws.

Non-Hodgkin's Lymphomas

Non-Hodgkin's lymphomas are a heterogeneous group of diseases characterized by monoclonal proliferation of malignant lymphoid cells in lymphoreticicular zones, including lymph nodes, bone marrow, spleen, liver and GIT.

Hodgkin's lymphoma (Hodgkin's disease)

Hodgkin's lymphoma (Hodgkin's disease) is a localized or disseminated malignant proliferation of cells of the lymphoreticular system, affecting primarily the tissue of the lymph nodes, spleen, liver and bone marrow. Symptoms of the disease include painless lymphadenopathy, sometimes with fever, night sweats, progressive weight loss, pruritus, splenomegaly and hepatomegaly. The diagnosis is based on lymph node biopsy.

Lymphomas

Lymphomas are a heterogeneous group of neoplastic diseases, the source of which are the reticuloendothelial and lymphatic systems. The main types of lymphomas are Hodgkin's lymphoma and non-Hodgkin's lymphomas.

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