Dettol

Dettol is an antiseptic with a disinfecting effect.

[1]

Indications of the dettol

Applicable in the following cases:

• processing of scratches with cuts or bites of various insects of primary, as well as primary-deferred nature;
• elimination of seborrhea, dandruff or acne;
• Treatment of wound surfaces for the prevention of bacterial infection.

[2]

Release form

The release is carried out in the form of an external solution, in bottles with a capacity of 125 and 250 ml, as well as in the form of a spray, in bottles with a capacity of 100 ml.

[3]

Pharmacodynamics

Chloro-xylene is a phenol derivative and has a disinfecting and antiseptic effect. Used externally.

In addition, chloroksilenol even in small concentrations has bactericidal activity against a large range of gram-positive and-negative microbes.

[4], [5], [6], [7]

Pharmacokinetics

After treating the skin with a drug, less than 50% of the chlorooxenol portion is absorbed into the blood, it is quickly synthesized there with a protein (this figure is 85-90%), and then metabolized (by 10-15%) with conversion to a catechinic or benzyl alcoholic structure.

So far it has not been possible to establish in which organ the metabolism of the substance takes place.

Excretion of most of the substance occurs in the urine - in the form of sulfate, as well as glucuronic conjugates in a ratio of 1 k6. The half-life of the drug is about 2-3 hours.

[8], [9], [10]

Dosing and administration

Scheme of application of solution.

The medicine is used externally - for children from 1 year old, as well as adults.

To treat scratches, and besides cuts and bites made by insects, it is required to wash the affected area with a medical solution (it is necessary to dissolve 50 ml of the drug in water (1 liter of water, 5% - 1k 20)), then cover the wound with bandage or dry gauze the bandage. When treating small wounds, a clean solution of the drug is allowed.

Acne should be rinsed twice a day. The solution is prepared according to the following scheme: 50 ml of the substance is diluted in warm water (also 1 l of water, 5% solution, 1k20). The duration of therapy is 2 weeks. Repeat the course can be appointed at least 7 days later.

To eliminate dandruff, you need to dissolve 25 ml of the drug in warm water (1 liter of water, obtaining 2.5% solution, the proportion is 1k40). It should be treated with medicine on the scalp and scalp for 10 minutes, after which it is rinsed with warm water and the head is washed. The medication is used once a day, for 2 weeks. To conduct a course is again allowed at least one week later.

As an additive for taking a bath in the treatment of acne on the body - it is required to dissolve 40 ml of medicinal substance in 125 liters of warm water. This course should last 2 weeks, the procedure is carried out once a day. Repeat therapy can be done after a minimum of 7 days.

Scheme of spray use.

Spray the affected area treated 1-2 times / day. If you need to remove excess excess liquid, you can use cotton or a piece of clean cloth.

This course continues, taking into account the clinical need for this medicine. Usually it lasts 1-2 weeks.

[13]

Use of the dettol during pregnancy

The use of Dettol does not affect the reproductive system. Also, there is no negative effect on the baby and fetus, but use of the drug in lactation or pregnancy is necessary after a careful correlation of the benefits and risks.

Contraindications

Among the contraindications:

• the presence of intolerance in relation to the elements of the medication;
• eczema, as well as contact dermatitis.

[11]

Side effects of the dettol

The use of drugs can cause skin irritation, manifested in the form of itching, flushing, and burning.

With the development of any side effects it is required to immediately abolish the use of the medication.

[12]

Interactions with other drugs

The spray is not incompatible with soap, as well as with other surfactants of anionic type, and in addition with iodides, tartrates, citrates and permanganates. This list also includes nitrates, silver salts and salicylates.

Storage conditions

Dettol solution can be contained in any conditions, but in a place that will not be accessible to young children.

The spray should be kept at temperature values not exceeding 30 ° C.

[14]

Shelf life

Dettol in the form of a medical solution can be used for 3 years after the release of the therapeutic agent, and the spraying life of the spray is 2 years.

Application for children

It is forbidden to prescribe medication to infants until 1 year.

Analogues

Analogues of the drug are such drugs as Antifungin with Gorosten, Dekasan and Virotek, and in addition Desmistin, Drapolen and Decamethoxin with Miramistin, Miramidez and Etoniy. Also included in this list is the ointment ointment and Octenisept.

[15], [16]