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Belosalik lotion
Medical expert of the article
Last reviewed: 03.07.2025
The combined drug Belosalik lotion is a topical corticosteroid agent used in dermatology to relieve inflammation, irritation, desquamation and pruritis of the skin.
ATC classification
Active ingredients
Pharmacological group
Pharmachologic effect
Indications Belosalik lotion
Belosalik lotion is intended for symptomatic treatment of chronic dermatoses with increased keratinization of epithelial keratinocytes and their desquamation (sloughing): allergic dermatoses (atopic dermatitis, urticaria, eczema); seborrhea and seborrheic dermatitis of the scalp; diffuse keratosis (ichthyosis); psoriasis of the scalp.
Release form
Belosalik lotion – solution in 50-100 ml bottles (with a dropper or spray nozzle) – for external use only.
Pharmacodynamics
The therapeutic effect of Belosalik lotion is provided by its active components – synthetic adrenal cortex hormone (corticosteroid) betamethasone in the form of dipropionate and salicylic (2-hydroxybenzoic) acid.
Betamethasone, when applied externally, helps relieve inflammatory, allergic and hyperproliferative reactions of the skin by binding to cell receptors and their DNA, which increases the synthesis of lipocortin protein, which inhibits the activity of the intracellular enzyme phospholipase A2. The further mechanism consists of blocking the release of arachidonic and lysophosphatidic acids and their subsequent modification by cyclooxygenases (COX 1 and COX 2) into active compounds - anti-inflammatory and inflammatory mediators (eicosanoids, prostaglandins, leukotrienes).
In addition, glucocorticosteroids (GCS), including betamethasone dipropionate, suppress the synthesis of T- and B-lymphocytes, tissue immunoglobulins (IgE and IgG), and also reduce the release of histamine from mast cells, which relieves the symptoms of an allergic reaction.
Salicylic acid in Belosalik lotion acts as an antiseptic and keratolytic, that is, it prevents infection from developing and softens dead skin particles.
Pharmacokinetics
A small amount of betamethasone in the Belosalik lotion enters the blood and binds to proteins; biotransformation of GCS occurs in the liver, and metabolites are excreted in the urine and feces.
Dosing and administration
Belosalik lotion is applied externally by spraying the solution onto the inflamed areas of the scalp - once or twice a day.
The maximum duration of use should not exceed three consecutive weeks.
Manufacturers warn against getting the drug into the eyes, on mucous membranes and genitals.
Use Belosalik lotion during pregnancy
Salicylic acid is contraindicated for pregnant women, and there is no evidence of the safety of topical corticosteroids for intrauterine fetal development. Therefore, Belosalik lotion is not used during pregnancy.
Contraindications
Belosalik lotion is contraindicated for use in the presence of:
- hypersensitivity to GCS and salicylates;
- skin lesions of bacterial, viral or fungal origin;
- acne and rosacea;
- purulent inflammatory foci and ulcers on the skin;
- skin irritation after vaccination;
- any skin problems in children during the first six months of life.
Side effects Belosalik lotion
Side effects of Belosalik lotion include:
The appearance of a skin reaction - redness, rash, burning and itching;
- increased dryness of the skin;
- formation of striae;
- inflammation of the hair follicles and hypertrichosis;
- thinning of the epidermal layer of the skin and its atrophy;
- addition of secondary infections.
Long-term use of this product, as well as large areas of its application, can cause dilation of skin capillaries, increased arterial and intracranial pressure, hyperglycemia and glucosuria, dyspepsia, disruption of fat and protein metabolism in the body, demineralization of bone tissue - that is, systemic side effects characteristic of GCS.
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Overdose
In case of exceeding the dose of Belosalik lotion, systemic side effects of glucocorticosteroids develop - adrenal cortex insufficiency and hypercorticism syndrome. The use of this drug should be stopped immediately and a doctor should be consulted.
Storage conditions
Belosalik lotion is recommended to be stored at normal room temperature out of the reach of children.
Shelf life
24 months.
Attention!
To simplify the perception of information, this instruction for use of the drug "Belosalik lotion" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.