Arachnodactyly belongs to the category of genetic pathologies, and currently medicine does not have methods for correcting gene defects. Therefore, treatment is directed to optimize the patient's condition, prevent the aggravation of pathology, and eliminate symptomatic manifestations. Complex therapy is prescribed, with the involvement of several medical specialists at once, which depends on the belonging of the most pronounced symptomatology: often, in addition, you have to contact an orthopedist, cardiologist, ophthalmologist, gastroenterologist and other doctors. 
Among the recommendations for the clinical management of patients, the following are considered as general principles:
- limiting physical activity, but not completely abandoning it (as part of supporting the cardiovascular system);
- drug therapy;
- if necessary, surgical correction of the most affected areas of the heart and blood vessels;
- orthopedic correction;
- spa treatment, physiotherapy, physiotherapy exercises.
The dietary food of patients with arachnodactyly should include a sufficient amount of high-protein foods, enriched with trace elements, vitamins, fatty acids. The use of meat, fish, seafood, beans, nuts is recommended. If arachnodactyly is due to homocystinuria, then the use of animal protein is sharply limited.
Children with a thin physique and tall stature are advised to introduce cottonseed and soybean oil, sunflower seeds, pork fat and lard into the diet from an early age. Additionally, they offer preparations containing polyunsaturated fatty acids of the Omega type, which inhibit the production of somatotropic hormone.
To normalize protein metabolism, B-group vitamins are prescribed. They can also be obtained from food: buckwheat, peas, liver.
It is very important that ascorbic acid enters the patient's body with food. For this purpose, rosehip infusion, bell pepper, cabbage, citrus fruits, as well as sea buckthorn, leeks are necessarily introduced into the diet.
If necessary, patients are offered orthopedic correction necessary to reduce the load on the spinal column and joints. For this purpose, orthopedic shoes, knee and other devices, instep supports, elastic bandages are used.
Surgical treatment is performed according to indications.
Drug treatment for arachnodactyly is carried out 1-2 times a year, which depends on the patient's condition and on the severity of pathological symptoms. The duration of the treatment course is determined individually and averages 4 months. 
To stimulate the formation of collagen, drugs Piaskledin 300, L-lysine or L-proline are prescribed in combination with complex multivitamin preparations containing ascorbic acid, B vitamins, tocopherol, magnesium, zinc, selenium, copper.
Among chondroprotectors, the most optimal use of chondroitin sulfate and glucosamine sulfate - drugs that are involved in regulating chondrocyte metabolism, suppressing enzyme synthesis, increasing the sensitivity of chondrocytes to enzyme effects, in stimulating anabolic processes, etc. Combined drugs are considered optimal such drugs: Teraflex, Artroflex, Artra etc.
Mineral metabolism is stimulated by drugs that normalize phosphorus-calcium processes. Active forms of vitamin D often become the medicines of choice: Alpha D 3 -Teva, Oxydevit, Bonviva, etc. At the same time, preparations of phosphorus, calcium, magnesium are used. During treatment, approximately once every 20 days, the level of calcium and phosphorus in the blood or urine is checked, and a blood test for alkaline phosphatase is performed.
To improve the bioenergetic state of the body, it is possible to prescribe Phosphaden, Riboxin, Lecithin, Elkar, Coenzyme Q10.
An approximate therapy regimen may look like this:
- Chondroprotector within the age dose, taken with food and sufficient water. The duration of one treatment course is 3-4 months.
- L-proline in a dosage of 500 mg (for children from 12 years old and adults) is taken half an hour before meals, 1-2 times a day, for six weeks. If indicated, an amino acid complex can be additionally prescribed - L-proline, L-lysine, L-leucine in an amount of 10-12 mg / kg of weight. Reception is carried out 1-2 times a day for two months.
- Vitamin-mineral complex preparations Centrum, or Vitrum, or Unicap, in dosage taking into account age. Duration of admission is 4 weeks.
This treatment regimen is appropriate if a patient with arachnodactyly complains of problems with the musculoskeletal system, and the test results indicate an increased excretion of glycosoaminoglycans in a 24-hour urine study and a decreased content of free amino acids in the blood.
As a rule, the treatment is perceived by patients well enough, without any special side effects. If hypersensitivity reactions are detected, the drugs are replaced, the treatment regimen is adjusted.
Physiotherapy procedures for arachnodactyly are prescribed according to indications. For example, with insufficient osteogenesis to improve the healing of bone fractures, or with signs of osteoporosis, electrophoresis with 5% calcium chloride, 4% magnesium sulfate, 2% copper sulfate or 2% zinc sulfate is recommended.
If vegetative vascular disorders are found, use 1% caffeine sodium benzoate, ephedrine hydrochloride or mezaton.
To activate the efficiency of the adrenal cortex, drug electrophoresis with 1.5% etymizole and decimeter therapy are prescribed to the adrenal glands. 
To stabilize the vascular tone, water procedures are recommended that promote vascular "gymnastics". Baths such as carbon dioxide, coniferous, hydrochloric, hydrogen sulphide, radon are excellent. They practice rubdowns, douches, contrast showers, foamy and salt baths.
To improve the condition of the cartilage tissue, magnetotherapy, inductotherapy, laser therapy, electrophoresis with dimethyl sulfaxide (Dimexidum) are used.
Surgical operations for arachnodactyly are prescribed strictly according to indications. For example, upon detection of pronounced hemodynamic disorders against the background of prolapse of the valve leaflets, massive aortic aneurysm, prosthetics of the valves and the damaged segment of the aorta are performed. 
If there are pronounced functional disorders of the respiratory and cardiovascular systems, resulting from a strong curvature of the chest, thoracoplasty is performed.
With progressive pain syndrome caused by a severe form of scoliosis of 3-4 degrees, surgical intervention is also indicated. From an ophthalmological point of view, subluxation of the lens complicated by secondary glaucoma, as well as cataracts and retinal degenerative changes with a high risk of detachment, are considered absolute indications for lens removal.
Any operation for patients with arachnodactyly and other disorders extending to the connective tissue structures is performed only at the stage of relative clinical and biochemical relief. After the intervention, long-term medical supervision and intensive therapy with the use of drugs that improve the exchange of connective tissue are required.