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Health

Serological tests

Toxocarosis: antibodies to Toxocara canis in serum

The main method of diagnostics of toxocarosis is the detection of IgG antibodies to Toxocara canis in the serum by ELISA with toxocar antigen in the study of blood serum in persons with a characteristic complex of symptoms: lymphadenopathy, hepatomegaly, bronchitis, bronchial asthma of unclear origin, urticaria rash against the background of eosinophilia of blood, leukemoid reaction eosinophilic type with a characteristic epidemic history (for example: geophagia), etc.

Echinococcosis: antibodies to the echinococcus in the blood

The EIA method is most effective for the diagnosis of echinococcosis. However, the use of this method is limited by the fact that many carriers of echinococcal cysts do not develop an immune response, antibodies in the blood are not formed. ELISA gives positive results in 90% of patients with cysts in the liver and only in 50-60% of patients with lung disease.

Giardiasis: the definition of antibodies to lamblia antigens in the blood

Existing ELISA test systems can detect separately specific antibodies of different classes (IgM, IgA, IgG) or total antibodies. Antibodies of IgM class to lamblia antigens are found in the blood on the 10-14th day after the invasion.

Toxoplasmosis: detection of antibodies IgM and IgG to toxoplasma in blood

Early diagnosis of toxoplasmosis is especially important for pregnant women due to the risk of intrauterine infection of the fetus, which can lead to fetal death (spontaneous abortion) or the birth of a child with serious lesions.

Amoebiasis: antibodies to Entamoeba histolytica in the blood

The diagnosis of intestinal amebiasis is established based on the detection of the pathogen in feces or tissues (examine the biopsy) using special dyes. In the feces, Entamoeba hystolitica antigens (adhesin) can be detected by ELISA.

Antibodies to Mycoplasma hominis in the blood

When using ELISA, antibodies of IgM and IgG classes can be determined for Mycoplasma hominis. This method is more sensitive and specific (92% and 95% respectively) than others.

Detection of Ureaplasma urealiticum antigen by direct immunofluorescence

Ureaplasma urealiticum is referred to as mycoplasmas. The name "ureaplasma" comes from the ability of this type of mycoplasma to synthesize the urease enzyme, which cleaves urea with the formation of carbon dioxide and ammonia.

Detection of Mycoplasma hominis antigen by direct immunofluorescence method

In men mycoplasma (Mycoplasma hominis, Ureaplasma urealyticum) most often cause urethritis, in women - endometritis and salpingitis, in newborns can cause meningitis, respiratory infections, septicemia.

Antibodies to Mycoplasma pneumoniae in the blood

Serological diagnosis is based on the detection of titer of antibodies to Mycoplasma pneumoniae in serum. The most widely used method was ELISA.

Respiratory Mycoplasmosis: Detection of the Mycoplasma pneumoniae Antigen by Direct Immunofluorescence

Mycoplasma pneumoniae is the causative agent of human respiratory tract diseases, parasitic on cell membranes. The specific gravity of respiratory mycoplasmosis in the general group of respiratory diseases varies for different population groups from 35% to 40%. Mycoplasmal pneumonia accounts for 10-17% of cases of total pneumonia.

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