Tablets that accelerate the metabolism for weight loss

, medical expert
Last reviewed: 10.08.2022

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Anyone who, at least once in his life, has been looking for ways to quickly and effectively eliminate excess body weight, knows that excess weight results from improper metabolism, poor diet and low physical activity. And to influence this process, you need tablets that accelerate the metabolism, for weight loss.

Indications of the tablets to accelerate metabolism

Tablets are indicated for admission for primary obesity in which the BMI can be 30+ kg / m 2 or 27+ kg / m 2 (if combined with other risk factors that result from excess weight (diseases such as insulin-dependent or 2- type diabetes mellitus or dyslipidemia)).

trusted-source[1], [2], [3], [4], [5], [6], [7]

Release form

In this article, consider the most popular means that accelerate the metabolism.

Xenical is available in capsules with a volume of 120 mg. One packet of tablets can contain 1, 2 or 4 blister packs. One blister contains 21 capsules.

Form release Reduxin - contour packs of 10 tab. On each.

Turboslim is produced in 20 or 60 tables. On the 1 st blister plate.

Names of tablets accelerating metabolism for weight loss

There are a number of drugs that help remove fat and speed up the process of metabolism, and they act without additional measures in the form of diets and various restrictions. Among them are the following drugs:

  • Reduxin and Goldlane help to influence the saturation center, prolong the time of action of the hormone responsible for saturation, have a lipolytic effect and accelerate the processes of metabolism;
  • Xenical and Orsoten block the enzyme of digestion, which promotes the absorption of fats - lipase;
  • Supplements such as Turboslim, and also LiDa, or MCC, etc., have diuretic and laxative properties, help to clear the intestines and liver, and also dilute the blood.

The properties of tablets for weight loss, accelerating the metabolism, are considered on the example of the drug Reduxin.

trusted-source[8], [9], [10], [11], [12], [13]


A combined agent that uses to treat obesity. Its active ingredient is sibutramine, a prodrug that acts in vivo through metabolic products (primary as well as secondary amines) that suppress the monoamine reuptake process (mainly norepinephrine and serotonin). Due to the increase in the content of neurotransmitters in synapses, the activity of the central nerve fibers of serotonin, together with adrenoreceptors, also increases, resulting in a feeling of saturation, a decrease in the need for food, and besides this, thermal production increases. Sibutramine indirectly triggers the action of β3-adrenergic receptors, thereby affecting brown fat tissue. Together with weight reduction, a decrease in triglycerides is observed, as well as an increase in the level of HDL in blood serum. Also, the level of LDL, total cholesterol and uric acid decreases.

Sibutramine, along with its metabolic products, does not affect the release of monoamines, nor does it inhibit MAO. In addition, it has no affinity for most neurotransmitter receptors, including serotonin, adrenergic receptors, and in addition benzodiazepine, dopamine, histamine, muscarinic, and NMDA receptors.

MCC is an enterosorbent, which has a sorption effect, and also has a nonspecific detoxification effect. It helps to bind, and in addition to deduce the products of activity of different microorganisms, and besides allergens, toxins having an internal or external nature, xenobiotics. In addition, it displays an excess of individual metabolites and metabolic products that respond to the appearance of an endogenous type of toxicosis.

trusted-source[14], [15], [16], [17]


After taking the medicine, sibutramine is rapidly absorbed from the digestive tract, at least 77%. Further, it undergoes the effect of per-systemic metabolism in the liver, and then biotransforms with the participation of the 3A4 CYP3A4 isoenzyme, resulting in the formation of 2 active metabolites (this is mono-, as well as didlesmethylsibutramine). The first with a single dose of 15 mg has a maximum concentration of 4 ng / ml (3.2-4.8 ng / ml), and the second - 6.4 ng / ml (5.6-7.2 ng / milliliter). The maximum concentration in the blood of sibutramine is reached after 1.2 hours, and the active metabolic products - after 3-4 hours. In the case of simultaneous consumption with food, the maximum concentration of metabolites is reduced by 30%, and the time to reach this index increases by 3 hours (AUC in this case does not change). Distribution in tissues occurs quickly. With plasma proteins, sibutramine binds to 97%, and the substance mono-, as well as didlesmethylsibutramine - by 94%. Equilibrium concentrations in the blood plasma active metabolic products reach 4 days after the initiation of therapy. This figure is almost 2 times higher than the plasma level after a single dose.

The half-life of sibutramine is 1.1 hours, the substances monodesmethylsibutramine and didesmethylsibutramine are 14 and 16 hours, respectively. There is a conjugation, as well as hydroxylation of active metabolites, resulting in inactive metabolites that are excreted from the body mainly through the kidneys.

trusted-source[18], [19], [20], [21]

Dosing and administration

Xenical should be taken on 1 tab. (120 mg) together with the basic daily meal (during the meal or at least one hour after it). In case of skipping meals or when eating fat is not allowed, you can skip the use of the drug.

Reduxin should be taken 1 p. / Day. Dosages are determined individually, this depends on the clinical effect, as well as the tolerability. At the beginning of treatment, a dosage of 10 mg is recommended; if poor tolerance is found, a dose of up to 5 mg can be lowered. Tablets are taken in the morning, they do not need to be chewed, only to drink with water. The medicine can be taken on an empty stomach or combined with food. If after 4 weeks. After the beginning of therapy there was no decrease in weight by 5 +%, the dosage should be increased to 15 mg / day.

Turboslim take 1 pp. / Day. On 2 tab. Before eating. Duration of treatment should be at least 1 month. If necessary, you can repeat the course.

trusted-source[29], [30], [31], [32]

Use of the tablets to accelerate metabolism during pregnancy

Preparations that accelerate the processes of metabolism, and used for weight loss, are forbidden to take during childbearing and breastfeeding.


Among the contraindications for taking Reduxin:

  • Pheochromocytoma;
  • Obesity caused by somatic diseases (eg, hypothyroidism);
  • Severe eating disorders (such as bulimia or anorexia nervosa);
  • Thyrotoxicosis;
  • Psychopathology;
  • Tourette's disease (or generalized tick);
  • Admission with MAO inhibitors (such as ephedrine, phentermine, and in addition fenfluramine, ethylamphetamine, as well as dexfenfluramine) or their use 2 weeks before the start of Reduxine; taking other drugs that affect the central nervous system (these may be neuroleptics or antidepressants); drugs that are prescribed in case of sleep problems (which contain the substance tryptophan), and in addition to this other drugs that reduce weight, with a central effect;
  • IHD, and in addition, chronic heart failure, heart defects in congenital form, various arrhythmias, tachycardia, peripheral arterial occlusive diseases, cerebrovascular pathologies (transient ischemic attack or stroke);
  • Uncontrolled increase in blood pressure (more than 145/90);
  • Severe disorders in the liver or kidneys;
  • Closed-angle form of glaucoma;
  • Confirmed by the diagnosis of dependence (on alcohol, drugs or drugs);
  • Benign prostatic hyperplasia;
  • The age is under 18 or over 65;
  • Revealed hypersensitivity to sibutramine or other components of drugs.

Xenical can not be taken with cholestasis or a syndrome of impaired absorption in a chronic form.

trusted-source[22], [23], [24]

Side effects of the tablets to accelerate metabolism

Side effects of Reduxin:

The organs of the CNS and PNS: mostly insomnia and dryness in the oral cavity; sometimes headaches, taste disorders, anxiety, dizziness, and paresthesia are possible; in some cases, there may be a state of drowsiness, depression, irritability or anxiety, as well as nervousness. In addition to this, cramps, pain in the back, emotional instability.

Organs of the cardiovascular system: rarely enough, there is an increase in blood pressure, tachycardia, acceleration of the heartbeat, as well as vasodilation.

Organs of the digestive system: mainly constipation and decreased appetite; In addition, in some cases, exacerbation of hemorrhoids or nausea.

Skin reactions: occasionally sweating, and in some cases - itching or skin hemorrhage.

General reactions: in some cases, the following disorders may occur: swelling, thirst, runny nose, bleeding, dysmenorrhea, acute form of interstitial nephritis, a decrease in the number of platelets.

Among the side effects of Xenical: mostly they arise from the gastrointestinal tract due to the pharmacological properties of the drug, which prevents the absorption of dietary fats. In most cases, patients noted the appearance of oily discharge from the rectum, gas separation, urgent urges for the act of defecation, an increase in this process, as well as incontinence and steatori. In general, these reactions were mild and transitory. Appeared usually at the early stage of therapy (the first 3 months), and in most cases, patients had a maximum of one episode of such a reaction. 

trusted-source[25], [26], [27], [28]

Interactions with other drugs

Reactions of Reduxine: inhibitors of monooxygenase oxidation, among which inhibitors of Ioenzyme 3A4 cytochrome P450 (such as ketoconazole, cyclosporine, and erythromycin), increase the plasma concentration of sibutramine metabolism products, while also increasing heart rate and QT interval (clinically insignificant).

Rifampicin, as well as antibiotics that are part of the macrolide group, and besides them phenytoin, phenobarbital, dexamethasone and carbamazepine accelerate the metabolism of sibutramine.

In the case of joint intake of several drugs that increase the blood serotonin content in the blood, a so-called. Serotonin syndrome. It occasionally occurs as a result of a combination of Reduxin with SSRIs (drugs treating depression), as well as individual remedies for migraine (such drugs as sumatriptan or dihydroergotamine). In addition, it may appear in the case of a compound with analgesics of strong action (this is pethidine, pentazocine, as well as fentanyl) or anti-cough medicines (eg, dextromethorphan). Sibutramine has no effect on oral contraceptive activity.

The combined intake of ethanol and sibutramine did not show an increase in the negative impact on the body of ethanol. But while drinking alcohol in the case of sibutramine for diet is strictly prohibited.

When you receive Xenical, you need to consider the possibility that the absorption of β-carotene, as well as vitamins A and D, as well as E and K, may decrease. Reducing weight as a result of Xenical therapy can increase the compensation of the metabolic process in people with diabetes, so they will need to reduce the dosage of oral glucose-lowering drugs.

trusted-source[33], [34], [35], [36], [37], [38], [39], [40]

Storage conditions

Diet pills that accelerate the metabolism should be kept in a place that is closed from children, moisture and sunlight. Temperature not more than 25 ° С.

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Shelf life

Medicines of this type can be used for 3 years from the date of manufacture.

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Doctor's comments

Regarding the safety and effectiveness of drugs containing sibutramine, the opinions of doctors are divided.

One part considers such drugs more dangerous than effective, because they negatively affect the human psyche, as well as the work of the heart. In defense of their theory, doctors state the following fact - such pills are banned in some countries, such as Canada, the US and Australia.

The second part believes that if the drugs are taken correctly, to comply with the dosage and recommendations of the doctor, they can really help get rid of excess weight, and completely safe. As proof, examples are given of the lives of people taking pills that have lost weight, and are now experiencing no problems.

Such a difference in the opinions of doctors should not be surprising, because sibutramine is a potent agent, so each organism can be influenced in different ways. If you do not take into account any contraindication - there will be no result. If the recommended dose is exceeded, side effects will begin. Therefore, it is necessary to follow the advice of the attending physician in all things and not try to heal yourself.

trusted-source[53], [54]

Reviews thin

Tablets, accelerating the metabolism, for weight loss are quite popular. Therefore, there are many reviews from people who were able to lose weight with the help of such drugs.

"My progress is not as impressive as that of many others, but I, too, can boast of positive changes in my weight, which occurred with the help of Reduxin. Without any additional measures, I started to drink these pills, and the weight began to go down - last month it took 4 kg, and for this - already 2. Therefore, I think that this medicine is really effective - with its help you can actually lose weight. "

"I got 20 extra pounds after the birth. I started to take Xenical, and also to keep to a diet and to be engaged in shaping - as a result for 6 months the excess weight left. These tablets to me have appointed or nominated the endocrinologist ».

"Xenical really helps. For 3 months my sister lost 10 extra pounds, just taking a pill once a day after a very tight dinner. In the afternoon I tried to eat only fruits and vegetables. And the result was achieved. If you do not have the desire to go in for sports or do not have time for it, then Xenical will suit you. "


To simplify the perception of information, this instruction for use of the drug "Tablets that accelerate the metabolism for weight loss" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.

Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.

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