Aspirin promotes weight loss
Last reviewed: 23.04.2024
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Salicylic acid, which is formed as a result of the splitting of aspirin, activates the cleavage of fat cells.
To aspirin has become a truly magical medical product, it remains to verify that it helps against AIDS.
At first glance, it may seem that the human race has been living with a medical product for more than 150 years from all diseases, not realizing its omnipotence. Not so long ago, scientists said that acetylsalicylic acid (aspirin) can be used to prevent cancer; At full blast, his beneficial effects on cardiovascular disease are being studied. And scientists from the Dundee Institute (England) inform the Science magazine that acetylsalicylic acid (aspirin) can also be used as a drug against obesity.
Acetylsalicylic acid originates from salicylic acid, which was used even by ancient Egyptians. In the second half of the 19th century, it was changed so that it did not damage the digestive system very much, and aspirin, which was released into mass production. Later, scientists established the mechanism of its anti-inflammatory and analgesic effects. At this time, researchers describe how aspirin has a great effect on cellular metabolism. Once in the body, aspirin is converted back to salicylic. Scientists have suggested that salicylic acid interacts with one of the main enzymes of metabolism by AMP-activated protein kinase.
This protein kinase is included in the accumulation of adenosine monophosphate, AMP, which is formed during the cleavage of high-energy ATP. In other words, the accumulation of AMP indicates an energy overexpenditure of the cell, and the enzyme switches its metabolism to the desired regime (including promotes the breakdown of fatty acids and prevents their synthesis). The scientists received mice in which one of the sites of the AMP-activated protein kinase mutated, after which the mice were injected with salicylic acid and observed what would happen to their fat deposits. It turns out that in the case of conventional mice, salicylic acid contributed to several times more active splitting of fat cells than in mice with a mutated enzyme. Thus, salicylic acid can actually affect metabolism and reduce the number of fat cells.
Scientists believe that aspirin also has an anti-cancer effect through the AMP-activated protein kinase. However, antidiabetics, which are also targeted at this enzyme, according to statistics, reduce the likelihood of developing a malignant tumor. It should be noted that the current work is not based on statistical results, but on the molecular mechanisms of the effect of a medical preparation, and, probably, acetylsalicylic acid is actually not so simple as it is commonly thought of
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