Tungsten Syndrome (DIDMOAD syndrome - Diabetes Insipidus, Diabetes Mettitus, Optic Atrophy, Deafness, OMIM 598500) is described for the first time by DJ Wolfram and N.R. WagenerB 1938 as a combination of juvenile diabetes mellitus and optical atrophy, which was subsequently supplemented with diabetes insipidus and deafness. To date, about 200 cases of this disease have been described.