Vitamin E when planning pregnancy for women and men: the norm, how to drink, the intake scheme

Even in the 20s of the last century, studies that were conducted on rats showed that exclusion of certain foods from the diet led to infertility. Adding salad leaves and wheat germ oil to food restored the reproductive function. Thus, vitamin E was discovered, and later the biologically active substance of vitamin α-tocopherol was described, which in Greek means "offspring, childbearing." This made it possible In 1938 to describe the chemical formula of tocopherol and synthesize it. Since then, it is widely used as a powerful antioxidant and a tool that enhances the function of male and female organs producing the production of sex cells. Therefore, the role of vitamin E in planning pregnancy is beyond doubt and important, both for women and men who are preparing to become parents.

Vitamin E for men when planning pregnancy

Preparing the body for future conception is necessary not only for women, but for men. 3-4 months before the planned event, to strengthen the reproductive function, to reduce the negative influences of the environment, to strengthen the protective properties of immunity, it is recommended to start taking a number of vitamins, including vitamin E. Vitamin E for men during pregnancy planning will prevent the cellular structure of the genital organs from damage and will provide high mobility and vitality of spermatozoa.

Vitamin E for Women in Pregnancy Planning

Vitamin E for women when planning pregnancy is very important, because. Will help to prepare the ovaries for the development of full-grown eggs, and after successful conception will reduce the risk of miscarriage, fetal fading, strengthen the placenta, help during the entire 40 weeks of pregnancy to feel good and supply the fetus with the necessary substances for its development. Other positive aspects of the role of vitamin E include:

• hormonal balance;
• improvement of blood microcirculation;
• stabilization of pressure;
• increased elasticity and strength of the muscular tissue of the uterus;
• decrease in the sugar level, which is very important for diabetics;
• strengthening of resistance against the penetration of infections into the reproductive system.

The norm of vitamin E in planning pregnancy

To determine the norms of vitamin E in planning pregnancy, it is necessary to understand the units of its measurement, tk. On some packages the abbreviation ME is specified, and on others - clear to all mg (milligramme). ME means the measurement of a substance in international units. To translate, if necessary from one unit to another, you need to apply the following formula:

1mg of vitamin E = 1.21 IU

The daily intake of vitamin E for women and men is different, but on average it is 10-20 IU. When planning pregnancy, experts recommend increasing to 200-400 IU, but the doctor must take the decision, taking into account individual health indicators and the human diet. It is worth taking into account the fact that with the products the vitamin also enters the body. So, most of it is contained in nuts (in 100g of various types of nuts from 5g to 25g of vitamin E), in dried apricots (5g), spinach, dogrose, wheat germ (2.5-3.8g), squid, 2.2g), salmon (1.8g), and others.

Indications of the vitamin E in the planning of pregnancy

The most important indication for the use of vitamin E in planning pregnancy is its beneficial effect on the reproductive organs. In addition, tocopherol increases:

• Immunity, protecting the body from various infections;
• elasticity and permeability of blood vessels;
• tissue regeneration.

In addition, vitamin E stabilizes the hormonal background, neutralizes the effects of harmful factors (smoking, alcohol), normalizes blood pressure, promotes the absorption of vitamin A, which also plays an important role in the body. If there are symptoms such as apathy, chronic fatigue, attention deficit, increased nervousness, headache, liver problems - this can be a signal of vitamin E deficiency in the body and an indication for its use. Also, unsuccessful attempts to conceive or endure a child - bells, indicating the need to saturate the body with vitamins, including tocopherol.

[1], [2], [3]

Release form

Vitamin E refers to fat-soluble vitamins. The form of its release is a capsule and an oil solution. The capsule shell is gelatinous, inside is a light yellow oily liquid. Packed in blisters and vials of different dosage: 100, 200 and 400 mg. The oily solution for injection is packaged in darkened vials with different concentrations of tocopherol (5%, 10%, 25%, 30%).

[4], [5], [6], [7], [8]

Pharmacodynamics

Pharmacodynamics of vitamin E is its antioxidant properties, its ability to influence the metabolism of cells, improve blood microcirculation. It increases the elasticity of blood vessels, prevents various disorders in the reproductive organs of men and women, prevents the penetration of infections and bacteria into the genitals, participates in the production of gonadotropin, a hormone that forms in the placenta during pregnancy and ensures its normal development. Also, the drug has a positive effect on cardiac activity, in particular on the myocardium, feeding it and improving its contractile activity. Vitamin E prevents anemia by participating in the synthesis of blood enzymes: hemoglobin, myoglobin, cytochrome, peroxidase, etc. It stimulates the synthesis of proteins, reduces the production of cholesterol by the liver, promotes the assimilation of vitamin A.

[9], [10], [11], [12]

Pharmacokinetics

The pharmacokinetics of vitamin E are as follows. Half of the whole used dose of the drug, getting into the gastrointestinal tract, is absorbed and reaches its maximum concentration in the blood after 4 hours. During absorption, it binds to lipoproteins, which transport the vitamin first to the lymph, and then into the bloodstream. It is concentrated in the adrenal glands, fat and muscle tissue, in the pituitary gland, liver, testes. After all metabolic processes, it is excreted with bile into the intestine, where the absorption of tocopherol continues. Everything that is not absorbed is excreted with feces. Metabolism products (tocopherolic acid and glucuronides) are excreted by urine.

[13], [14], [15], [16], [17], [18]

Dosing and administration

The way of application and the dose of vitamin E in planning pregnancy should be calculated by the doctor and directed to saturate the body with vitamin, prepare the woman for a long period of bearing the fetus, to protect her and the future child from the influence of various harmful factors.

Daily doses for future parents greatly exceed the daily requirement of the body and often cause fear. But poisoning is possible when taking the drug in a dosage, a thousand times higher than recommended.

When preparing for pregnancy not giving birth to women or having no problems with the previous bearing, it is enough to take 100-200 IU daily. If there were miscarriages, placental detachment, fetal fading, premature birth or there are gynecological diseases, the dose increases to 200-400 IU.

For men, they recommend taking 300 IU per day. Surveys of pregnant women testify that the most convenient form of packaging the drug is capsules, especially since they most likely exist in the dosage that is needed (100, 200, 300, 400 IU).

The scheme of taking vitamin E during pregnancy planning is as follows: the required dose is evenly divided into two portions and taken in the morning and evening. How much to drink vitamin E at planning of pregnancy, will define or determine the doctor in view of all parameters. Typically, the minimum period of 1-2 months, but the reception can continue for half a year, until the conception of the child.

[22], [23], [24]

Folic acid and vitamin E in pregnancy planning

Folic acid (vitamin B9) and vitamin E when planning pregnancy are two powerful tools that can prepare a woman's body for increased stress during pregnancy and form healthy fetal organs. Folic acid is necessary for the development of the circulatory and immune systems, the normal formation of the neural tube of the fetus. For men, vitamin B9 is needed for the production of viable spermatozoa. In natural conditions, folic acid enters the body with food, and is also produced by the intestinal microflora. To products containing vitamin, include legumes, liver, yeast, black bread from a meal of coarse grind, green vegetables, especially spinach, sorrel, is present in honey. Completely meet the need for folic acid through food is hampered by the fact that as a result of heat treatment part of the vitamin is destroyed. The daily intake of folic acid is 400 mkg.

The properties of vitamin E are mentioned above, we emphasize only its powerful antioxidant and immunological characteristics. With the help of this tool, not only the future mother will take care of her offspring, but also the pope.

[25], [26], [27], [28]

Contraindications

The first contraindication to the use of vitamin E is hypersensitivity to the drug. So, in any case, you can read the instructions. Allergists also argue that tocopherol does not in itself cause allergic reactions. Since it is often taken with vitamin A (retinol), the histamine reaction to retinol is not deservedly attributed to vitamin E. However, the reaction of the body in the form of nausea, vomiting, diarrhea, skin rashes, itching, pain in the stomach, rarely - dry mouth and bleeding gums and is considered a sign of allergy to the drug. There are also warnings for patients with thyroid gland hyperfunction, diabetes mellitus, cholecystitis, hemophilia, liver cirrhosis, kidney disease.

[19]

Side effects of the vitamin E in the planning of pregnancy

Side effects of vitamin E in the planning of pregnancy can occur with uncontrolled reception of the drug. The most negative of them is a decrease in prothrombin in the blood (hypoprothrombinemia). This is expressed in poor blood coagulability, which leads to bleeding of the gums, mucous nasal, genital organs. It is also possible to increase blood pressure, exacerbation of chronic liver disease, pancreatitis.

[20], [21]

Overdose

An overdose of vitamin E can occur with long-term administration of large doses, significantly exceeding those recommended for use. This can lead to headaches, digestive system disorders (nausea, diarrhea, abdominal pain), fatigue, increased blood pressure.

[29], [30], [31], [32]

Interactions with other drugs

Interactions with other preparations of vitamin E are as follows: it "makes friends" with vitamin A, because protects it from oxidation, and with vitamin C, which protects it from oxidation, together with selenium enhance the antioxidant effect of each other. When interacting with drugs, it has been found that drugs such as xenical, cholestramine, gastal with simultaneous administration reduce the absorption rate of the vitamin.

[33], [34], [35], [36], [37], [38], [39]

Storage conditions

Vitamin E is stored in a dry, dark place, at a temperature not exceeding 25 degrees.

[40], [41], [42], [43]

Shelf life

Shelf life different manufacturers indicate different (2 or 3 years). It is necessary to look at the package so as not to harm yourself with a spoiled drug.

[44], [45], [46]

Reviews

Most of all positive responses about vitamin E from women who had problems with conception. Their chance to become a mother, they connect with the reception of this particular drug. Those who at the planning stage took it along with folic acid and other vitamins, and successfully passed the way from pregnancy to the birth of a healthy child, can not unequivocally attribute their success to this particular drug.